Excision of a Large Gastrointestinal Stromal Tumour Following 16 Months of Neoadjuvant Therapy with Imatinib (Case Report).

Introduction: Although the standard treatment for stromal tumours is surgery, in locally advanced forms, it is often necessary to achieve tumour downstaging to improve surgical outcomes. Neoadjuvant treatment in gastrointestinal stromal tumours (GISTs) with tyrosine kinase inhibitors, including imatinib, has been shown to be effective in several studies, but the duration of this treatment is still a subject of debate.

Case Report: We report a case of a large GIST of the stomach in a 51-year-old patient with atypical presentation that was initially unresectable.

Paraneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report.

Introduction: Pyoderma gangrenosum is a rare, idiopathic, inflammatory, neutrophilic dermatitis characterized by sterile skin ulceration. It can be associated with an underlying pathology, especially inflammatory bowel disease and hematological malignancies. Its association with a malignant pathology in the context of a paraneoplastic syndrome is more commonly described in hematological malignancies, with solid tumors being rare.

Meckel's diverticulum strangulated in an umbilical hernia.

Background: Strangulated Meckel's diverticulum (MD) in an umbilical hernia (UH) is a rare event. We present herein a case of strangulated MD in UH in a child.

Case Report: An 18-month girl was admitted with clinical features suggesting upper intestinal strangulation since seven days.

[Prophylactic splenectomy to prevent complications of splenomegaly in children with sickle cell anemia?].

Objective: To assess the effects of splenectomy in children with sickle cell anemia and to propose a therapeutic approach to splenomegaly in sickle cell anemia.

Material And Method: This retrospective study, conducted in the pediatric surgery department of the Tokoin Teaching Hospital in Lomé, included 8 children followed for sickle cell anemia (hetero- and homozygous) and who were admitted from January 1987 through December 2004 for splenic rupture or referred for prophylactic splenectomy.

Results: The patients' mean age at splenectomy was 9 years 6 months.

[Meckel's diverticulum in children: eleven cases].

We report 11 cases of Meckel's diverticulum in children admitted to the department of Paediatrics Surgery of Lomé (Togo). None of the cases was identified before surgery. A systematic search during appendectomy identified 3 cases.

[Buruli ulcer in Togo: a hospital study].

Buruli ulcer is an emerging disease with a high prevalence in many West African countries neighbouring Togo. The aim of the present study is to assess the situation in Togolese hospitals. It was conducted for 2 years (between January 2000 and December 2001) based on the Buruli ulcer record files set up in Togolese hospitals, with a view to analyse the incidence of the disease, its characteristics in the patients and its topographic distribution in relation to their environment.

[Treatment of inguinal hernia under local anesthesia at the Central University Hospital of Lome].

In our search study, we were allowed to do 74 opérations of inguinal hernia (71 indirect and 3 femoral hernia). All these patients were operated under local anaesthesia with zylocaine 2%. The dose was between 4 to 40 ml.