Publications by authors named "Attila Levente Gergely"

Fiber-based sorbent materials are an essential part of containing oil spills, thus preventing ecological damage. Poly(styrene--isobutylene--styrene) thermoplastic elastomer fibers were successfully produced by centrifugal spinning. Scanning electron microscopy revealed that the fibers were bead free and smooth-surfaced, with an average fiber diameter of 5.

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Lavender oil (LEO) is one of the most well-known essential oils worldwide which, besides its extensive application in aromatherapy, serves as raw material for various fields, including the food, cosmetic, and pharmaceutical industries. Accordingly, several global requirements were established to warrant its quality. Microencapsulation represents an emerging technology widely applied for the preservation of essential oils, simultaneously providing new ways of application.

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An amorphous fiber-based solid dispersion of chlorzoxazone was prepared for the first time by employing centrifugal spinning, using polyvinylpyrrolidone as the fiber-forming polymer. After optimization of the spinning parameters, the obtained fibers were characterized using a set of analytical techniques, both in a solid- and solution-state. Morphological characterization revealed a slightly aligned, defect-free fibrous structure with an average fiber diameter of d = 3.

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Aceclofenac-loaded polyvinylpyrrolidone fiber-based amorphous solid dispersion was produced successfully by centrifugal spinning. The solution concentration and rotational speed were optimized to produce the fiber-based drug carrier system, with a determined production rate of 12.7 g/h dry solid fibers.

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Fibrous structures are promising candidates for oil-water separation applications. In this study, we have produced poly(styrene--isobutylene--styrene) thermoplastic elastomeric fibers with the centrifugal spinning fiber production method. The optimal fiber production conditions were achieved when using a 25% / solution concentration in an 80/20 tetrahydrofuran/toluene (/) solvent system at 8000 rpm rotational speed.

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Lapatinib (Lap) is a lypophilic drug frequently used in cancer treatment; however, due to its limited solubility and permeability, achieving therapeutic dose through oral administration proves to be a challenge. There are various methods for enhancing the solubility of Lap and other similar drugs, one being the preparation of amorphous solid dispersions (ASD). In this study, a Lap-loaded polyvinylpyrrolidone (PVP) fiber mat was created with centrifugal spinning from a PVP/Lap solution in dimethyl formamide and ethanol.

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