Improving stabilization of α-tocopherol and α-tocopheryl acetate against oxidation, light and UV radiation by complexation with β-cyclodextrin and starch.

Unlabelled: Despite the remarkably high antioxidant activity of tocopherols, their applications in the food industry are limited because of their instability under various conditions. Complexes of α-tocopherol (α-TQ) or α-tocopheryl acetate (α-TQA) with β-cyclodextrin (β-CD) or starch were prepared and characterized by UV-vis, IR and thermal analysis. Oxidative stability of α-TQ and α-TQA against HO was 74.

Comparative analysis of PI and fuzzy logic controller for grid connected wind turbine under normal and fault conditions.

This research is dedicated to improving the control system of wind turbines (WT) to ensure optimal efficiency and rapid responsiveness. To achieve this, the fuzzy logic control (FLC) method is implemented to control the converter in the rotor side (RSC) of a doubly fed induction generator (DFIG) and its performance is compared with an optimized proportional integral (PI) controller. The study demonstrated an enhancement in the performance of the DFIG through the utilization of the proposed FLC, effectively overcoming limitations and deficiencies observed in the conventional controllers, this approach significantly improved the performance of the wind turbine.

Assessment of a new protocol strategy to control the ectoparasitic infestation in Nile tilapia (Oreochromis niloticus) using efficient natural products.

This study aimed to evaluate alternative in vivo treatment trials using natural products for ectoparasitic infestation on Nile tilapia; these two products were not previously used in the treatment of parasitic fish diseases. So, a total of 400 Oreochromis niloticus (O. niloticus) fish measured 10-15 cm in length; 350 from a fish farm in (Kafr Elsheikh and 50 from Nile River (Al Bahr Al Aazam), Egypt.

Design, Synthesis and Molecular Modeling of Pyrazolo[1,5-]pyrimidine Derivatives as Dual Inhibitors of CDK2 and TRKA Kinases with Antiproliferative Activity.

Background: The increasing prevalence of drug resistance in cancer therapy underscores the urgent need for novel therapeutic approaches. Dual enzyme inhibitors, targeting critical kinases such as CDK2 and TRKA, represent a promising strategy. The goal of this investigation was to design, synthesize, and evaluate a set of pyrazolo[1,5-]pyrimidine derivatives for their dual inhibition potential toward CDK2 and TRKA kinases, along with their potential antiproliferative against cancer cell lines.

Diagnostic and therapeutic approach to endobronchial metastases from extra-thoracic neoplasms: A report of three cases and brief review of literature.

Introduction: Endobronchial metastases (EBMs) are rare, with primary tumours predominantly of breast, renal, and colorectal origin. Bronchoscopy is the diagnostic gold standard, with histological confirmation through immunohistochemical study.

Cases: We presented three cases of EBMs, one secondary to colorectal cancer and two associated with renal tumours.

Diagnostic innovations in Equine Parasitology: a Nanogold-ELISA for sensitive serodiagnosis of migratory strongylus vulgaris larvae infections.

Strongylus vulgaris, a devastating parasitic nematode in equids, causes life-threatening verminous aneurysms that are challenging to diagnose early. This study pioneered integrating nanotechnology into an indirect enzyme-linked immunosorbent assay (i-ELISA) system to enhance the sensitivity and specificity for detecting S. vulgaris larval antigens in equine serum samples, with PCR confirmation of the species.

Retraction: Cefotaxime incorporated bimetallic silver-selenium nanoparticles: promising antimicrobial synergism, antibiofilm activity, and bacterial membrane leakage reaction mechanism.

[This retracts the article DOI: 10.1039/D2RA04717A.].

Pancreaticoduodenectomy with pancreaticogastrostomy and an external pancreatic stent in risky patients: a propensity score-matched analysis.

Background: There is an ongoing debate about the most appropriate method for reconstructing the pancreas after a pancreaticoduodenectomy (PD). This study assessed the impact of pancreaticogastrostomy (PG) with an external pancreatic stent on postoperative outcomes following PD in high-risk patients.

Patients And Methods: This study involves a propensity score-matched analysis of high-risk patients who underwent PD with PG reconstruction.

Synergistic antitumor effects of atorvastatin and chemotherapies: In vitro and in vivo studies.

Atorvastatin (ATOR) acts on certain antitumor pathways; the consequences of chemotherapies continue to be a major concern, notwithstanding the increased efficacy provided by contemporary therapies. This study investigated the synergistic effects and underlying mechanisms of different treatment protocols using ATOR on the THP-1 cell line and on lung cancer in mice. For the in vitro study, an MTT assay was performed, and then different combinations against the THP-1 cell line were used as follows: non-treated cells, THP-1/ATOR IC, THP-1/cytarabine (CYT) IC, THP-1/doxorubicin (DOX) IC, THP-1/DOX/CYT, THP-1/ATOR/CYT, THP-1/ATOR/DOX, and THP-1/ATOR/CYT/DOX.

Using the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Prognostic Markers for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis of Observational Studies.

Obstructive sleep apnea (OSA) is a chronic condition characterized by the partial or complete collapse of the airways during sleep, leading to hypoxemia (reduced oxygen flow to organs) and disrupted sleep. This study aims to establish robust evidence for the relationship between the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) and the severity and prognosis of OSA. A systematic review and meta-analysis were conducted using PubMed, Cochrane Central Register of Controlled Trials, Scopus, Medline, and Web of Science to gather all relevant articles.

Maximizing solar distillation performance for conical solar still through varied energy storage materials.

The study investigates the performance enhancement of a conical solar distillation system by incorporating different energy storage materials, including glass balls, stainless steel balls, sandstones, and black gravel. These materials were analyzed based on their ability to improve energy and exergy efficiencies. The experimental setup involved using identical sizes (∅ 1.

Evaluation of different inflammatory markers during the infection of domestic cats (Felis catus) by Cystoisospora felis (Coccidia: Apicomplexa).

Background: Cystoisospora felis or Isospora felis is a ubiquitous apicomplexan protozoon parasite infecting domestic cats worldwide.

Objectives Of The Study: this study aims to identify the causative agent of diarrhea in cats by determining several elevating stressors caused by these coccidian protozoans with molecular characterization. So, from January 2023 to April 2023, a total of 370 domestic cats were hospitalized at various clinics in the Cairo and Giza Governorates.

Enhancement of AVR system performance by using hybrid harmony search and dwarf mongoose optimization algorithms.

Innovations in control algorithms, integration of smart grid technologies, and advancements in materials and manufacturing techniques all push the boundaries of AVR performance. As the demand for power systems progresses with the complexity and variety of loads, conventional AVR designs may struggle to handle these ever-changing circumstances efficiently. Therefore, the need for new optimization methods is crucial to bolstering the efficiency, reliability, and adaptability of AVRs.

Liposomes and Their Therapeutic Applications in Enhancing Psoriasis and Breast Cancer Treatments.

Psoriasis and breast cancer are two examples of diseases where associated inflammatory pathways within the body's immune system are implicated. Psoriasis is a complex, chronic and incurable inflammatory skin disorder that is primarily recognized by thick, scaly plaques on the skin. The most noticeable pathophysiological effect of psoriasis is the abnormal proliferation of keratinocytes.

Modification of chitosan-ethyl formate polymer with zinc oxide nanoparticles and β-CD to minimize the harmful effects of Alternaria early blight on Vicia faba.

Derivatives of chitosan-ethyl formate polymers (Chs-EF) show promise as biologically relevant materials. The novelty of this study lies in the innovative use of Chs-EF doped with zinc oxide nanoparticles and beta-cyclodextrin, which significantly enhances the polymers' protective activities against Alternaria early blight disease in Vicia faba by improving both disease resistance and plant health. After doping Chs-EF with zinc oxide nanoparticles (ZnONPs) and inserting it into the beta-cyclodextrin (CD), two products emerged: Chs-EF/ZnONPs and Chs-EF/CD.

Correction: Sustainable polymeric adsorbents for adsorption-based water remediation and pathogen deactivation: a review.

[This corrects the article DOI: 10.1039/D4RA05269B.].

Foam separation of radio-molybdenum oxyanions (MoO) incorporated into Co(II)/Al(III) layered double hydroxide using anionic surfactant.

Foam separation of radio-molybdenum oxyanions (MoO) incorporated into in-situ formed Co(II)/Al(III) layered double hydroxide (LDH) particles was applied for recovery of these anionic species from aqueous solutions. The results showed that Co(II)/Al(III) molar ratios of 2 and 2.5 resulted into not only high recovery values for MoO (R > 0.

Unlocking vinpocetine's oncostatic potential in early-stage hepatocellular carcinoma: A new approach to oncogenic modulation by a nootropic drug.

The development of new drugs for the inhibition of hepatocellular carcinoma (HCC) development and progression is a critical and urgent need. The median survival rate for HCC patients remains disappointingly low. Vinpocetine is a safe nootropic agent that is often used to enhance cognitive function.

An innovative approach to control fish-borne zoonotic metacercarial infections in aquaculture by utilizing nanoparticles.

Fish-borne zoonotic trematodes (FBZTs) pose significant health risks and economic challenges worldwide. This study investigated the prevalence of encysted metacercariae (EMCs) in Nile tilapia (Oreochromis niloticus) from two Egyptian governorates and evaluated the antiparasitic efficacy of chitosan, silver, and selenium nanoparticles against these parasites. A cross-sectional analysis of 453 O.

A New approach for simultaneous detection and photocatalytic degradation of imidacloprid and dinotefuran in water using terbium-based fluorometry and mixed-phase TiO.

This study explores a novel method for detecting neonicotinoid insecticides, imidacloprid (IMD) and dinotefuran (DNT), in water using terbium (Tb) ions photo probe. The optimal excitation and emission wavelengths for Tb luminescence were identified at 310 nm and 545 nm, respectively. The influence of pH and solvent on Tb-complex fluorescence was investigated.

Magnetic self-doped TiO /FeO@g-C solar-driven photocatalytic composite for water decontamination.

Declining water resources and their contamination with chemicals risk the aquatic environment. Therefore, this work was devoted to designing a magnetically recyclable photocatalyst suitable for water treatment, namely, a TiO /FeO@g-C composite. Different preparation conditions were investigated together with the corresponding characteristics.

Antibacterial and anticancer potential of bioactive compounds and secondary metabolites of endophytic fungi isolated from .

Fungal endophytes are known to produce bioactive chemicals and secondary metabolites that are often identical to those produced by their host plants. The main objective of the current study was to isolate and identify endophytic fungi associated with the medicinal plant , and to investigate their potential antibacterial and anticancer properties. The ethyl acetate extracts from the isolated endophytic fungi, as well as the host plant , were subjected to bioactivity assays to evaluate their antibacterial and anticancer potential against multi-drug resistant bacterial strains and the human hepatocellular carcinoma cell line HepG2.

Sustainable polymeric adsorbents for adsorption-based water remediation and pathogen deactivation: a review.

Water is a fundamental resource, yet various contaminants increasingly threaten its quality, necessitating effective remediation strategies. Sustainable polymeric adsorbents have emerged as promising materials in adsorption-based water remediation technologies, particularly for the removal of contaminants and deactivation of water-borne pathogens. Pathogenetic water contamination, which involves the presence of harmful bacteria, viruses, and other microorganisms, poses a significant threat to public health.