Publications by authors named "Attia Kotb"

Microplastics pose a serious ecological threat to agricultural soils, as they are very persistent in nature. Microplastics can enter the soil system in different ways and present different shapes and concentrations. However, little is known about how plants react to microplastics with different concentrations and shapes.

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Lassa virus genome consists of two single-stranded, negative-sense RNA segments that lie in the genus Arenavirus. The disease associated with the Lassa virus is distributed all over the world, with approximately 3,000,000-5,000,000 infections diagnosed annually in West Africa. It shows high health risks to the human being.

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Cystic echinococcosis (CE) is a worldwide zoonotic public health issue. The reasons for this include a lack of specific therapy options, increasing antiparasitic drug resistance, a lack of control strategies, and the absence of an approved vaccine. The aim of the current study is to develop a multiepitope vaccine against CE by in-silico identification and using different Antigen B subunits.

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NF-Y is a class of heterotrimeric transcription factor composed of three subunits; NF-YA, NF-YB, and NF-YC. This complex binds to the CCAAT box found in eukaryotic promoters and is involved in the plant development and proliferation at various stages. Although many studies were conducted on NF-Y gene family in various species, but no study has been reported yet in switchgrass (Panicum virgatum L.

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(Herbst) (Coleoptera: Tenebrionidae) is the most destructive pest of stored grain commodities. To control the attack of this insect pest, it is important to develop non-hazardous alternatives to replace fumigants. This study examined the fumigant toxicity and repellent activity of seven essential oils (, , and ) against adult under controlled laboratory conditions.

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  • The study focuses on the relationship between root architecture and the Gibberellic acid-sensitive (GA-sensitive) Rht genes in wheat, particularly their role in improving drought tolerance and plant growth.
  • Out of 200 wheat genotypes analyzed under normal and osmotic stress conditions, significant differences were found in the number of seminal roots and overall root/shoot growth, indicating that genotypes with GA-sensitive Rht13 gene performed better than those with GA-insensitive Rht1 gene.
  • Specifically, certain genotypes showed enhanced root systems (up to 5 seminal roots) and improved growth metrics under stress, suggesting that the presence of GA-sensitive Rht genes is beneficial for nutrient uptake from deeper soil layers.
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Background: The bZIP transcription factor family, characterized by a bZIP domain, plays vital roles in plant stress responses and development. While this family has been extensively studied in various plant species, its specific functions in Camelina sativa (False Flax) remain underexplored.

Methods And Results: This study identified 71 bZIP transcription factors in C.

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Drought stress poses a critical threat to global crop yields and sustainable agriculture. The GASA genes are recognized for their pivotal role in stress tolerance and plant growth, but little is known about how they function in sunflowers. The investigation aimed to identify and elucidate the role of HaGASA genes in conferring sunflowers with drought tolerance.

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  • - The CRISPR/Cas9 system has been applied to edit specific genes in HD and K326 tobacco cultivars, optimizing the system to target lignin and pectin synthesis genes (Ntab06050 and Ntab0857410).
  • - Eight constructs for lignin-related genes and five for pectin-related genes were created; targeting was guided by identifying PAM sequences for effective editing.
  • - Successful mutations of the targeted genes resulted in mutation frequencies of 6.2% for pectin-related NtabGAUT4 and 9.4% for lignin-related NtabCCoAMT.
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  • - In mid-latitude rice systems, mineral nitrogen fertilizers are crucial but lead to significant nitrogen losses, prompting the need for better soil organic matter management and sustainable practices to improve nitrogen efficiency and crop yields.
  • - A study evaluated the effects of combining mineral urea with organic fertilizers (farmyard manure and poultry compost) on various rice genotypes (NUYT-1 to NUYT-6) at Pakistan's National Agricultural Research Centre.
  • - Results showed that using poultry compost along with mineral urea notably increased nitrogen content in soil and plants, boosted shoot and root growth, and enhanced overall crop productivity, with an optimal N application strategy involving a mix of organic and mineral sources.
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CPSF30, a key polyadenylation factor, also serves as an mA reader, playing a crucial role in determining RNA fate post-transcription. While its homologs mammals are known to be vital for viral replication and immune evasion, the full scope of CPSF30 in plant, particular in viral regulation, remains less explored. Our study demonstrates that CPSF30 significantly facilitates the infection of turnip mosaic virus (TuMV) in , as evidenced by infection experiments on the engineered mutant.

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Chitin is the second most prevalent polysaccharide found in nature, following cellulose. Amino-oligosaccharides, the byproducts of chitin degradation, exhibit favorable biological properties and potential for various uses. Chitinases play a crucial function in the breakdown of chitin, and their exceptionally effective production has garnered significant interest.

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  • Mountain landscapes, like those in Pir Chinasi National Park, face fragmentation from human activities (tourism, urbanization) and natural events (floods, landslides, climate change); the study focuses on this impact over 25 years.
  • A survey of 200 residents revealed that 60% noticed pressures on local vegetation, while NDVI analysis showed significant vegetation degradation, with over 34% of the area suffering from some level of land deterioration.
  • The research also noted that temperature increases correlate with vegetation changes, and although some areas saw improvements in plant cover, human activities were a major factor affecting the ecosystem.
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The nutritional quality improvement is among the most integral objective for any rice molecular breeding programs. The seed storage proteins (SSPs) have greater role to determine the nutritional quality of any cereal grains. Rice contains relatively balanced amino acid composition and the SSPs are fractioned into albumins (ALB), globulins (GLO), prolamins (PRO) and glutelins (GLU) according to differences in solubility.

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Tomato ( L.) is one of the most widely consumed and produced vegetable crops worldwide. It offers numerous health benefits due to its rich content of many therapeutic elements such as vitamins, carotenoids, and phenolic compounds.

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  • * The study investigated the effects of biochar application on wheat varieties (FSD08 and PUNJAB-11) under salinity stress, using different sodium chloride levels and biochar concentrations.
  • * Results showed that biochar significantly mitigated the negative impacts of salt on growth and yield, and enhanced the plant's self-defense mechanisms, suggesting it as a beneficial amendment for sustainable crop production in saline conditions.
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Breeding high yielding water-deficit tolerant rice is considered a primary goal for achieving the objectives of the sustainable development goals, 2030. However, evaluating the performance of the pre-breeding-promising parental-lines for water deficit tolerance prior to their incorporation in the breeding program is crucial for the success of the breeding programs. The aim of the current investigation is to assess the performance of a set of pre-breeding lines compared with their parents.

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Farmers are using municipal wastewater either treated or untreated for irrigation because of limited fresh water resources. Wastewater extensively used for irrigation purposes is enriched with many nutrients. The reuse of wastewater is imposing a negative impact on human health and the ecosystem.

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Background: Bladder cancer (BLCA) poses a significant global health challenge due to its high incidence, poor prognosis, and limited treatment options.

Aims And Objectives: This study aims to investigate the association between two specific polymorphisms, CYP1A2-163 C/A and CYP1A2-3860G/A, within the Cytochrome P450 1A2 (CYP1A2) gene and susceptibility to BLCA.

Methods: The study employed a case-control design, genotyping 340 individuals using Polymerase Chain Reaction-High-Resolution Melting Curve (PCR-HRM).

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The rapid global emergence of antibiotic resistance genes (ARGs) is a substantial public health concern. Livestock manure serves as a key reservoir for tetracycline resistance genes (TRGs), serving as a means of their transmission to soil and vegetables upon utilization as a fertilizer, consequently posing a risk to human health. The dynamics and transfer of TRGs among microorganisms in vegetables and fauna are being investigated.

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  • Heavy metals like cadmium are harmful to both plants and people, and researchers are focusing on this issue.
  • Iron is really important for plants, but there's not enough of it in the soil because it often doesn't dissolve well.
  • A study showed that using FeO nanoparticles can help plants grow better even when they are exposed to cadmium, especially at a lower dose of 20 mg/L.
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  • Climate change is seriously impacting agriculture by causing shifts in cropping patterns and introducing abiotic stresses like extreme temperatures, drought, and salinity, which threaten global food security.
  • Plant hormones, particularly salicylic acid (SA), play a key role in helping plants cope with these harsh conditions, and this review delves into the genetics and molecular mechanisms of how SA works to mitigate damage from abiotic stresses.
  • The review also discusses potential advancements in genetic engineering, like CRISPR technology, to enhance plant resilience to climate change, emphasizing the importance of SA in promoting sustainable agriculture in challenging environments.
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