Introduction: Undernourished persons with tuberculosis (TB) (PWTB) are at increased risk of mortality, treatment failure and relapse. Nutritional support for PWTB has the potential to mitigate the risk of undernutrition. However, given ethical concerns, well-powered randomised control trials of macronutrient support are unavailable to inform policymakers, clinicians and researchers about the impact of nutritional support.
View Article and Find Full Text PDFDrug-resistant tuberculosis (DR-TB) poses a significant public health challenge, particularly in resource-limited settings. The prevalence and management of DR-TB in African countries require comprehensive strategies to improve patient outcomes and control the spread of the disease. Aggregated routine data (from 2018 to 2022) on multidrug-resistant TB (MDR-TB) were collected from the National TB Programs (NTPs) from all six countries.
View Article and Find Full Text PDFOver the past 15 years, and despite many difficulties, significant progress has been made to advance child and adolescent tuberculosis (TB) care. Despite increasing availability of safe and effective treatment and prevention options, TB remains a global health priority as a major cause of child and adolescent morbidity and mortality-over one and a half million children and adolescents develop TB each year. A history of the global public health perspective on child and adolescent TB is followed by 12 narratives detailing challenges and progress in 19 TB endemic low and middle-income countries.
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