Publications by authors named "Atsuo Nakamae"

Article Synopsis
  • The study investigates the mechanisms behind chronic knee osteoarthritis pain and pain after knee surgery, focusing on brain connectivity, specifically involving the anterior insular cortex (aIC).
  • Fifteen patients with knee osteoarthritis underwent magnetic resonance imaging and clinical assessments before and six months after knee arthroplasty, along with 15 matched control patients for comparison.
  • Results revealed that changes in resting-state functional connectivity (rs-FC) between the aIC and specific brain regions correlated with pain levels, suggesting that rs-FC may help understand knee OA and postoperative pain.
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Article Synopsis
  • - This study examines how ACL reconstruction affects medial meniscal extrusion (MME) during weight-bearing activities, as abnormal mechanical stress can lead to meniscus issues post-surgery.
  • - Seventeen patients who had unilateral ACL reconstruction and 20 healthy volunteers were evaluated through ultrasonography and MRI before and after the surgery to assess MME and knee function.
  • - Results showed that while MME in resting positions didn’t change significantly, there was an increase in MME during standing and walking after the ACL surgery, indicating altered knee mechanics under stress compared to healthy individuals.
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Purpose: The purpose of this study was to reveal the changes in the shape of the posterior femoral condyle and the morphology of the ACL, both before and after epiphyseal closure. The hypothesis of this study is that the morphological change of the posterior femoral condyle and that of the ACL may be correlated to some extent.

Methods: Eighty-one patients who underwent surgery for the knee joint (meniscal repair, arthroscopic synovectomy, medial patellofemoral ligament reconstruction) between 2016 and 2021 were included in this study, 48 patients aged 13 years or under (before epiphysis closure; mean age: 10.

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Purpose: To investigate whether the pivot-shift test reflects patient-reported outcomes 1 year after anterior cruciate ligament (ACL) reconstruction based on a multicentre prospective cohort study.

Methods: This study included patients who underwent primary ACL reconstruction using the hamstring tendons. The pivot-shift test grades were determined according to the International Knee Documentation Committee (IKDC) form as 0, 1+, 2+ or 3+.

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The purpose of this study was to investigate factors that influence clinical outcomes after anterior cruciate ligament (ACL) reconstruction in patients aged ≥40 years. We studied 264 patients aged ≥40 and 154 patients aged ≤20 years who underwent ACL reconstruction at several surgical centers. A logistic regression analysis was conducted to identify factors that influenced the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 1 year post-ACL reconstruction.

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Background: The influence of vision on multi-joint control during dynamic tasks in anterior cruciate ligament (ACL) deficient patients is unknown. Thus, the purpose of this study was to establish a new method for quantifying neuromuscular control by focusing on the variability of multi-joint movement under conditions with different visual information and to determine the cutoff for potential biomarkers of injury risk in ACL deficient individuals.

Methods: Twenty-three ACL deficient patients and 23 healthy subjects participated in this study.

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Article Synopsis
  • Epiphyseal injuries on the femoral side are a significant issue in pediatric ACL reconstruction, leading to the common use of the OTTR method, which has shown good clinical outcomes.
  • A cadaver study suggested that the OTTR method may have poorer rotational stability compared to anatomical single bundle reconstruction.
  • The report introduces a new surgical technique that preserves the ligament remnant by re-attaching it to the posterolateral bundle footprint, aiming to enhance rotational stability in pediatric ACL surgeries.
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Article Synopsis
  • Meniscal injuries are a common source of knee pain and may require surgery, but MRI used for diagnosis can be inaccurate, leading to false results.
  • This study compares needle arthroscopy—a newer technique that allows direct viewing of knee structures—to MRI and traditional diagnostic arthroscopy in diagnosing meniscal injuries in 40 patients.
  • Results show that needle arthroscopy provides moderate agreement with diagnostic arthroscopy and may be a more accurate alternative than MRI, especially for lateral meniscus injuries.
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Background The discoid lateral meniscus (DLM) is a unique anatomical variant characterized by a larger, thicker lateral meniscus. For clinical diagnosis of DLM, coronal and sagittal slices in two-dimensional (2D) MRI and arthroscopic imaging are typically employed. However, evaluating the entire shape of the DLM is challenging due to the limited views and details provided by these methods.

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  • - The study aimed to systematically review how capsular repair during hip arthroscopy affects patient-reported outcomes and the need for total hip arthroplasty (THA) in individuals with femoroacetabular impingement syndrome.
  • - Researchers analyzed 5 studies involving 639 patients, comparing outcomes for those who underwent capsular repair versus those who did not, using the modified Harris Hip Score as a measurement tool.
  • - Results indicated that capsular repair showed a positive impact on patient-reported outcomes (standardized mean difference of 0.42) and was linked to a reduced need for conversion to THA, but did not significantly lower the revision surgery rates.
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The pilot study aimed to determine whether the time from injury to surgery influences on postoperative knee biomechanics during walking in patients with anterior cruciate ligament reconstruction (ACLR). Thirty-two patients with unilateral ACLR (early, 10 patients; delayed, 22 patients) and 30 control subjects participated in this study. All examinations for patients with ACLR were performed preoperatively and at 12 months postoperatively and comprised passive knee joint laxity, knee muscle strength, and knee kinematics and kinetics during walking.

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Purpose: Medial meniscus extrusion is one of the risk factors for knee osteoarthritis (OA). However, lateral meniscus extrusion has not been discussed, and detailed information remains unknown. In particular, the lateral meniscus has high mobility and is expected to be difficult to evaluate in terms of its behavior under static conditions.

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Article Synopsis
  • Nineteen patients were divided into two groups: one received EMD during surgery, and the other did not, with evaluations done at several time points post-surgery.
  • While the EMD group showed less tunnel widening at two weeks, by 12 months, there was no significant difference between the two groups regarding tunnel widening or clinical outcomes.
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The Japanese Orthopaedic Association National Registry (JOANR) is Japan's first national registry of orthopaedic surgery, which has been developed after having been selected for the Project for Developing a Database of Clinical Outcome approved by the Health Policy Bureau of the Ministry of Health, Labour and Welfare. Its architecture has two levels of registration, one being the basic items of surgical procedure, disease, information on surgeons, surgery-related information, and outcome, and the other being detailed items in the affiliated registries of partner medical associations. It has a number of features, including the facts that, because it handles medical data, which constitute special care-required personal information, data processing is conducted entirely in a cloud environment with the imposition of high-level data security measures; registration of the implant data required to assess implant performance has been automated via a bar code reader app; and the system structure enables flexible collaboration with the registries of partner associations.

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The purpose of this study is to evaluate the clinical results of over-the-top route (OTTR) reconstruction for pediatric anterior cruciate ligament (ACL) injuries and compare them with results of anatomic single-bundle reconstruction (SBR), which used the bone tunnel technique and was performed early after epiphyseal closure (age ≤15 years). This study included pediatric patients aged 11-15 years who underwent ACL reconstruction. The mean age at surgery was 13.

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Background: Motion analysis can be used to evaluate functional recovery after anterior cruciate ligament (ACL) reconstruction; however, the biomechanics parameters of the lower limb that are specifically altered in ACL-reconstructed knees compared to the contralateral side are not well understood. This retrospective study aimed to compare side-to-side differences in lower limb biomechanics during the first 100 milliseconds (ms) after initial contact in a single-leg forward landing task.

Methods: Using three-dimensional motion analysis, lower joint kinematic and kinetic variables were measured 8-10 months postoperatively in 22 patients who had undergone ACL reconstruction.

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Background: Anterior cruciate ligament (ACL) injury is the most common traumatic injury to the knee joint. Suspensory fixation has become popular in ACL reconstruction because of its high primary stability, less invasiveness, and surgical convenience. There are two common types of suspensory fixation devices: those with fixed-length and those with adjustable-length loops.

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Background: During anterior cruciate ligament (ACL) reconstruction, even when a posterior wall of the femoral bone tunnel is identified, computed tomography (CT) occasionally demonstrates a breach of the posterior femoral cortex of the femoral bone tunnel, i.e., posterior wall blowout, after ACL reconstruction (posterior wall blowout-like phenomenon).

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Background: Inhibitions in the acquisition of accurate information about the environment can affect control of the lower extremities and lead to anterior cruciate ligament injury. This study aimed to clarify the effects of limited prior knowledge of the height of the fall, as well as limited visual input, on lower limb and trunk motion and ground reaction force during landing.

Methods: Twenty healthy university students were recruited.

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Purpose: In revision anterior cruciate ligament reconstruction (ACLR), our procedure of choice is the over-the-top route (OTTR) for cases where it is difficult to use a primary bone tunnel or to create a new bone tunnel due to the enlargement or malposition of the bone tunnel. Depending on the condition of the primary bone tunnel, we choose single (bone tunnel or OTTR) or double (bone tunnel or anteromedial (AM) bundle: OTTR /posterolateral (PL) bundle: bone tunnel) for femoral fixation. This study showed the results of single and double OTTR revision ACLR using the hamstring tendon.

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Background: Knee joint distraction (KJD) has received much attention as a joint preserving surgery, especially in young patients with advanced knee osteoarthritis (OA).

Methods: This study included 16 patients with advanced knee OA who underwent KJD combined with marrow stimulating techniques and were followed up for more than 2 years. The patients' clinical scores, including the Japanese Orthopaedic Association (JOA) score, Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales, ROM, joint space width, and semiquantitative MRI were evaluated.

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Purpose: The objective of this study was to investigate factors that influence the prevalence of medial and lateral meniscal injuries at the time of anterior cruciate ligament (ACL) reconstruction in patients with ACL injuries.

Methods: Patients with ACL injuries at 9 institutions were enrolled in this multicentre study. Age, sex, duration between injury and surgery, pivot shift test grade, anterior knee laxity determined using the Kneelax 3 arthrometer, and other variables were assessed by logistic regression analysis.

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Background: Posterior cruciate ligament (PCL) degeneration is often seen in knee osteoarthritis (OA); however, there is no established method for its evaluation. The purpose of this study is to investigate whether the Hounsfield unit (HU) using computed tomography (CT) could be a useful scale to evaluate the degeneration of PCL in knee OA.

Methods: Knee OA treated with total knee arthroplasty (21 patients, 21 knees) and non-osteoarthritic knees (21 patients, 21 knees) were retrospectively observed and studied.

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Background: The posterior cruciate ligament (PCL) is one of the essential stabilizers of the knee joint and it was demonstrated that its degenerative change related to the knee osteoarthritis (OA). We aimed to evaluate signal of the PCL in OA patients in comparison with healthy young and elderly volunteers using the ultra-short echo timeenhanced (UTE)-T2∗ mapping, and to validate these findings with histology.

Methods: Thirty asymptomatic volunteers, 13 young people (younger group) and 17 elderly people (elder group), and 27 patients who had undergone total knee arthroplasty (OA group) were enrolled in this study.

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