Effects of reference axes used during measurements of ocular and corneal higher-order aberrations in patients following LASIK.

Purpose: To determine the effects of the reference axes used during the measurements of ocular and corneal higher-order aberrations (HOAs) in patients before and after laser in situ keratomileusis (LASIK).

Methods: Wavefront sensing and corneal topography were determined for 29 eyes of 15 patients before and after LASIK. Ocular and corneal HOAs were calculated for 4-mm- and 6-mm-diameter pupils with the instrument aligned with the line of sight (LOS) or with the vertex normal (VN).