Involvement of the Multidrug and Toxic Compound Extrusion Transporter in Testosterone Release from Cultured Pig Leydig Cells.

Testosterone is considered to be released from Leydig cells via passive diffusion because of its hydrophobicity; however, the exact mechanism underlying testosterone secretion and the transporter involved are both unknown. Multidrug and toxic compound extrusion (MATE) transporters are predominantly found in the kidneys and liver and are thought to function in the elimination of metabolic organic cations during the final step of excretion in the kidney. In contrast, mMATE2 has been shown to be predominantly expressed in testicular Leydig cells.

Delineation of malignant glioma by turbo spin echo multislice motion-sensitized driven-equilibrium (TSE-MSDE) with gadolinium-based contrast media: a case report.

T1-weighted images by turbo spin echo multislice motion-sensitized driven-equilibrium with gadolinium-based contrast media clearly delineated the brainstem invasion of a malignant glioma in an 80-year-old woman compared with other magnetic resonance imaging sequences.

Brain stem and cerebellar atrophy in chronic progressive neuro-Behçet's disease.

Purpose: Chronic progressive neuro-Behçet's disease (CPNBD) resembles multiple sclerosis (MS) on patient background and image findings, and therefore is difficult to diagnose. The purpose is to identify the characteristic magnetic resonance imaging (MRI) findings of CPNBD and to clarify the differences between the MRI findings of CPNBD and those of MS.

Materials And Methods: The subjects consist of a CPNBD group (n=4; 1 male and 3 females; mean age, 51 y.

Reversible distension of the subarachnoid space around the optic nerves in a case of idiopathic hypertrophic pachymeningitis.

Idiopathic hypertrophic pachymeningitis (IHP) is a chronic inflammatory disease of unknown cause. We report a case of IHP with bilateral distended subarachnoid space (SAS) of the optic nerves and unilateral visual disturbance. We observed marked amelioration of magnetic resonance (MR) imaging findings after initiation of treatment with prednisolone.

Focal deformity of the cranial nerves observed on multislice motion-sensitized driven equilibrium (MSDE) in patients with neurovascular compression.

Objective: Our purpose is to demonstrate the deformity of the cranial nerves by arterial compression using a novel technique, multislice motion-sensitized driven equilibrium (MSDE).

Methods: Subjects were 10 patients with neurovascular compression (5 patients with trigeminal neuralgia and 5 patients with hemifacial spasm). We observed the existence and extent of deformity of nerves by MSDE.

Inverse-direction scanning improves the image quality of whole carotid CT angiography with 64-MDCT.

Purpose: The purpose of this prospective study was to clarify whether reducing the incidence of perivenous artifacts through craniocaudal scanning improves the quality of 64-multidetecter computed tomography (MDCT) angiography images of the whole carotid artery.

Methods: Forty patients underwent MDCT angiography in the caudocranial (n=20) or craniocaudal (n=20) direction in 2007. All patients were injected with 75 ml of contrast media followed by a 35-ml saline chaser bolus at 4.