Publications by authors named "Atsuko Motojima"

Article Synopsis
  • Two new furanone-containing compounds, linfuranones B and C, were discovered from a plant-associated actinomycete called Sphaerimonospora.
  • Their structures were analyzed using NMR and MS techniques, with their configurations determined through various chemical methods.
  • Both linfuranones B and C promoted the differentiation of preadipocytes into mature fat cells at concentrations of 20-40 μM, without causing any cell toxicity.
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Two new compounds, robillafuran and (+)-robillapyrone, were isolated from the culture extract of a fungal strain of Robillarda along with (+)-monascuspyrone. The absolute configuration of (+)-robillapyrone and (+)-monascuspyrone was determined by ECD calculation. These three compounds showed preadipocyte differentiation activity at 10-40 μM.

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Three new cyclic pentadepsipeptides, hikiamides A-C (1-3), were isolated from the culture extract of Fusarium sp. TAMA 456. The structures were determined by spectroscopic analysis using NMR and MS, and the absolute configurations were established by using Marfey's method and chiral HPLC analysis.

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