Age-related changes of elements in human corpus callosum and relationships among these elements.

To elucidate compositional changes of the corpus callosum with aging, the authors investigated age-related changes of elements and relationships with their element contents in the corpus callosum. After ordinary dissection by medical students at Nara Medical University was finished, the genu, trunk, and splenium of the corpus callosum were resected from the subjects ranging in age from 58 to 94 years. The element contents of the corpus callosum were determined by inductively coupled plasma-atomic emission spectrometry.

Increases of calcium, phosphorus, and magnesium in both the right and left fibrous trigones of human heart with aging.

To elucidate compositional changes of the cardiac skeleton with aging, the authors investigated age-related changes of elements in both the right and left fibrous trigones of human heart by inductively coupled plasma atomic emission spectrometry (ICP-AES). After ordinary dissection by medical students was finished, hearts were resected from the subjects and both the right and left fibrous trigones were removed from the hearts. The subjects consisted of 10 men and 13 women, ranging in age from 62 to 99 years.

Silicon intake to vertebral columns of mice after dietary supply.

Vertebral columns were dissected and analyzed after birth with oral administration of silicon for 4 wk and for 8 wk. The silicon level was lower (20 microg/g) at the beginning. It remains unchanged after 4 wk and then increases twice as much as that for those mice bred for 8 wk than those bred for 4 wk.