A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of Well Parent Japan in routine care in Japan: The training and nurturing support for mothers (TRANSFORM) study.

Background: Well Parent Japan (WPJ) is a new hybrid group parent training programme combining sessions to improve mothers' psychological well-being with a culturally adapted version of the New Forest Parenting Programme (NFPP). This study investigates the effectiveness and cost-effectiveness of WPJ against treatment as usual (TAU) within Japanese child mental health services.

Methods: TRANSFORM was a pragmatic multi-site randomised controlled trial (RCT) with two parallel arms.

The Effectiveness and Cost-effectiveness of Well Parent Japan for Japanese Mothers of Children With ADHD: Protocol for a Randomized Controlled Trial.

Background: Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder associated with numerous functional deficits and poor long-term outcomes. Internationally, behavioral interventions are recommended as part of a multimodal treatment approach for children with ADHD. Currently, in Japan, there are limited interventions available to target ADHD.

Effectiveness of a Parent Training Programme for Parents of Adolescents with Autism Spectrum Disorders: Aiming to Improve Daily Living Skills.

Parent training (PT) has been well established in younger children with autism spectrum disorder (ASD) but is less well studied in adolescents. This study examined the effects of attempting PT to enhance the daily living skills (DLSs) of adolescents with ASD. Twenty-five parents of adolescents with ASD participated in either the immediate- or delayed-treatment control condition.

Effectiveness of a Teacher Training Program for Students with Symptoms of Developmental Disorders: Data from a Correspondence High School in Japan.

In the present study, a teacher training program based on behavioral therapy was conducted for high school correspondence course teachers of adolescents aged between 15 and 18 years who showed developmental difficulties. Participating teachers were assigned to either an immediate treatment (IT; = 13) or delayed treatment control (DTC; = 17) group to evaluate the effectiveness of the program, which comprised five 90-min sessions with small groups of three to six participants and was conducted over three months. The results showed significant improvement in students' behaviors and social responsiveness and in teachers' confidence among those in the IT group; however, those in the DTC group did not show any such improvement.

Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice.

Background: Parkinson's disease (PD) is an age-related progressive neurodegenerative disorder caused by selective loss of dopaminergic neurons from the substantia nigra (SN) to the striatum. The initial factor that triggers neurodegeneration is unknown; however, inflammation has been demonstrated to be significantly involved in the progression of PD. The present study was designed to investigate the role of the pro-inflammatory cytokine interleukin-1 (IL-1) in the activation of microglia and the decline of motor function using IL-1 knockout (KO) mice.

Effect of a physical activity improvement program using the transtheoretical model at a small-scale company.

The present study aimed to investigate the potential use of the transtheoretical model (TTM) by clarifying the program's effects on workers at a small-scale company. Subjects were 22 male workers at a communication system company. They were divided into two physical activity improvement program groups, the TTM-based assistance group (TTM group, n=12) and the control group (n=10).

[Effects of shift work on quality of sleep among retired workers].

To examine the relationship between shiftwork experience and quality of sleep after retirement, we carried out a self-reported questionnaire survey on 777 retired workers of a manufacturing company. Questionnaire items included past illness, current health status, dietary habit, alcohol drinking, smoking, regular exercise, sleep, working condition (job, shift work experience, shift work periods and side job), current working status, social activity, educational background, sex, age and number of years since retirement. Present health status (adjusted odds ratio 4.