Publications by authors named "Atsuko Awaji"

Beckwith-Wiedemann syndrome (BWS) is a representative imprinting disorder. Gain of methylation at imprinting control region 1 (ICR1-GOM), leading to the biallelic expression of IGF2 and silencing of H19, is one of the causative alterations in BWS. Twenty percent of BWS patients with ICR1-GOM have genetic defects in ICR1.

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Article Synopsis
  • The study examines the physical growth outcomes of very low birth weight infants born before 30 weeks gestation, comparing those with and without intrauterine growth restriction (IUGR).
  • Male and female participants were categorized based on their growth status (small for gestational age and appropriate for gestational age), and their body weight, length, and BMI were measured at various ages.
  • Results indicate that SGA boys consistently had lower body weight and BMI, while SGA girls had lower body weight and length; neither group showed significant improvement in weight or BMI from 1 to 6 years.
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Although magnesium (Mg) contents are different between breast milk and formula, few studies have investigated the blood Mg level in breast fed or formula fed preterm infants. We examined the influence of feeding type on serum Mg and whole blood ionized Mg (iMg) levels in preterm infants soon after birth. We included 115 preterm infants born between gestational weeks 32 and 35.

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Background: To investigate the relationship between early-life stress and glucocorticoid receptor (GR) gene methylation, which may result in long-lasting neurodevelopmental impairment, we performed a longitudinal analysis of the methylation ratio within the GR gene promoter 1F region using next-generation sequencing in preterm infants.Cell-free DNA was extracted from the frozen serum of 19 preterm birth infants at birth and at 1 and 2 months after birth. All were admitted to the neonatal intensive care unit of Juntendo University Shizuoka Hospital between August 2014 and May 2016 and suffered from chronic lung disease (CLD).

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