Publications by authors named "Atsama Marie Amougou"
Article Synopsis
- Mortality in children accounts for 15% of global AIDS-related deaths, with Cameroon facing a higher rate of 25%, mainly due to poor viral response.
- A study analyzed viral suppression (VS) among Cameroonian children and young adults receiving antiretroviral therapy (ART) to identify factors affecting VS, finding an overall rate of 82.3%.
- Key findings revealed that younger age, longer ART duration, and certain non-DTG-based regimens were independent predictors of non-VS, suggesting the need for prioritizing transition to DTG-based regimens to improve outcomes.
Article Synopsis
- - Hepatitis E virus (HEV) is a key cause of acute viral hepatitis globally, with a significant outbreak first identified in North-Cameroon, yet there's limited molecular research on it in the region.
- - This study focused on analyzing serum samples from the outbreak, utilizing real-time RT-PCR and nested RT-PCR to detect and sequence HEV RNA.
- - Results indicated that 20 out of 24 samples tested positive for HEV RNA, with phylogenetic analysis revealing most cases belonged to HEV genotype 1 (subtype 1e) and some to genotype 3 (subtype 3f), thus enhancing the understanding of HEV in Cameroon.
Background: Hepatitis E virus (HEV) is a zoonotic pathogen of which pigs have been established as reservoirs. In the present study, we investigated the presence of HEV among pigs in the Center and Littoral regions of Cameroon and performed the molecular characterization of positive strains.
Methodology: A total of 453 serum and stool samples were randomly collected from pigs in slaughterhouses in Obala, Douala and Yaounde.
Objective: The aim of this study was to update the data on the prevalence of anti-HDV antibodies in Cameroon.
Results: Antibodies against hepatitis Delta virus (Anti-HDV) were found in 16.48% (95% CI 11.
Introduction: Hepatitis E virus (HEV) is one of the most prevalent cause of acute hepatitis in humans worldwide. The risk of HEV transmission is not limited only to spread from human to human but the infection can also spread from animals to humans, especially from the domestic pigs. Despite mounting evidence regarding the zoonotic potential of porcine HEV infection, there are limited data on its prevalence in pigs in the sub-Sahara Africa region.
View Article and Find Full Text PDFThe in vitro antioxidant properties, cytoprotective activity, and ability to induce nuclear translocation of nuclear factor E2-related factor-2 (Nrf-2) of five solvent fractions of the methylene chloride/methanol (1:1 v/v) extract of Khaya grandifoliola (Meliaceae) and Entada africana (Fabaceae) were evaluated. Five antioxidant endpoints were used in the antioxidant activity investigation. The total phenolic content of the fractions was assessed as to the Folin-Ciocalteu method and the profile of interesting fractions analyzed by high-performance liquid chromatography (HPLC).
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