Publications by authors named "Atrin Yousefizadeh"
Pharmacol Res
October 2022
Article Synopsis
- Many clinical trials on anti-amyloid agents for Alzheimer's disease have failed, calling the amyloid hypothesis into question.
- Researchers are now focusing on microglia, non-neuronal cells that are crucial for brain development and synaptic remodeling, as potential targets for new treatments.
- The review discusses how microglia contribute to synaptic loss and neuroinflammation in Alzheimer's, suggesting that targeting these cells could lead to effective disease-modifying therapies.
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