Discovering allatostatin type-C receptor specific agonists.

Currently, there is no pesticide available for the selective control of the pine processionary moth (Thaumetopoea pityocampa-specific), and conventional methods typically rely on mechanical techniques such as pheromone traps or broad-spectrum larvicidal chemicals. As climate change increases the range and dispersion capacity of crop and forest pests, outbreaks of the pine processionary occur with greater frequency and significantly impact forestry and public health. Our study is carried out to provide a T.

Anti-diabetic and anti-inflammatory bioactive hits from Matsum. stem and (Blanco) Merr. & Rolfe bark through bioassay-guided fractionation and liquid chromatography-tandem mass spectrometry.

Women have been found to be at a higher risk of morbidity and mortality from type 2 diabetes mellitus (T2DM) and asthma. α-Glucosidase inhibitors have been used to treat T2DM, and arachidonic acid 15-lipoxygenase (ALOX15) inhibitors have been suggested to be used as treatments for asthma and T2DM. Compounds that inhibit both enzymes may be studied as potential treatments for people with both T2DM and asthma.

Machine learning prediction for COVID-19 disease severity at hospital admission.

Importance: Early prognostication of patients hospitalized with COVID-19 who may require mechanical ventilation and have worse outcomes within 30 days of admission is useful for delivering appropriate clinical care and optimizing resource allocation.

Objective: To develop machine learning models to predict COVID-19 severity at the time of the hospital admission based on a single institution data.

Design, Setting, And Participants: We established a retrospective cohort of patients with COVID-19 from University of Texas Southwestern Medical Center from May 2020 to March 2022.

Population structure and insecticide resistance status of Tuta absoluta populations from Turkey.

Background: Tuta absoluta is a devastating pest in tomato production areas worldwide. After its first introduction to Turkey in 2009, it quickly became the major pest of tomato-growing areas. Although some biocontrol agents have been used, especially in greenhouses, the main control of T.

Trends in utilization of deceased donor kidneys based on hepatitis C virus status and impact of public health service labeling on discard.

Background: Kidneys from deceased donors infected with hepatitis C virus (HCV) are underutilized. Most HCV virus-infected donors are designated as Public Health Service increased donors (PHS-IR). Impact of PHS and HCV designations on discard is not well studied.

PAPP-A concentrations change in patients with gestational diabetes.

Our aim was to assess the relationship between gestational diabetes and glucose intolerance regarding maternal serum PAPP-A and free β-hCG concentrations in first trimester pregnancies. This study was conducted on 278 women between 18-45 years old with singleton pregnancies. The subjects were divided into four groups, according to their 50 and 100 g OGTT results.

A Huge Fetal Sacrococcygeal Teratoma with a Vascular Disruption Sequence.

Fetal sacrococcygeal teratomas (SCTs) occur in one to two per 20 000 pregnancies that cause high-output cardiac failure. High-output cardiac failure leads to polyhydramnios, hydrops, intrauterine fetal demise and preterm birth. Vascular disruption defects refer to those involving the interruption or destruction of some part of the fetal vasculature.

Double notches: association of uterine artery notch forms with pregnancy outcome and severity of preeclampsia.

Objective: To assess uterine artery Doppler waveforms and notches performed in the third trimester as a predictor of adverse outcomes.

Methods: Of 490 preeclampsia (PE) patients between 24 and 34 weeks gestation, 166 were diagnosed with mild PE and 324 were diagnosed with severe PE. Patients were divided into four groups (no notch, a unilateral notch, bilateral notches and double notches).

Role of endometrial power Doppler ultrasound using the international endometrial tumor analysis group classification in predicting intrauterine pathology.

Purpose: To assess the contribution of the terms and definitions recently described by international endometrial tumor analysis (IETA) group when evaluating endometrial lesions on power Doppler imaging.

Methods: Patients requiring endometrial sampling were examined prospectively by transvaginal B-mode and power Doppler sonography (PDS) the day before scheduled diagnostic procedure. Sonographic features were classified using IETA group classification.

Management of a Klippel-Trenaunay syndrome in pregnant women with mega-cisterna magna and splenic and vulvar varices at birth: a case report.

Klippel-Trenaunay syndrome (KTS) is a rare, sporadic and complex malformation characterized by the clinical triad of: (i) capillary malformation (port-wine stain); (ii) soft tissue and bone hypertrophy or occasionally, hypertrophy of one lower limb; and (iii) atypical lateral varicosity. The maternal and fetal risks associated with pregnancy in women with KTS are proportional to disease severity, which can be exacerbated by pregnancy. Complications include bleeding, disseminated intravascular coagulation, thromboembolic events and pain.

Hyberbaric oxygen increases atresia in normal & steroid induced PCO rat ovaries.

Background: In this study, we investigated the effect of hyperbaric oxygen therapy (HBOT) on the morphology of estradiol valerate (EV) induced polycystic ovary (PCO) to find a new treatment modality for improvement of PCO.

Methods: The rats were divided into four groups. Group1, control; group 2, PCO group; group 3, PCO with HBOT group and group 4, normal ovary with HBOT.

Vascular endothelial growth factor gene +813CC polymorphism of foetus is associated with preterm labour but not with pre-eclampsia in Turkish pregnant women.

We investigated the effect of polymorphism at +813 locus of vascular endothelial growth factor (VEGF) gene on predisposition to preterm labour and pre-eclampsia (PE). We examined polymorphism of the VEGF +813 gene of foetuses from umbilical cord blood in 31 cases of preterm labour, 34 pre-eclamptic and 58 healthy term labour. VEGF +813 gene polymorphisms were studied using a polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis.

Remission of endometriosis by hyperbaric oxygen treatment in rats.

We designed this prospective, randomized controlled animal study to determine the effects of hyperbaric oxygen (HBO) on experimentally induced endometriosis in a rat model. Surgical induction of endometriosis was performed in 40, nonpregnant, female, Wistar-Albino rats at the Experimental Medicine Research Center of Istanbul University (DETAE). Four weeks later, the first and second laparotomies for volume measurement and peritoneal fluid (PF) collection were performed, and the rats were divided randomly into the study and control groups.

Craniorachischisis with a variant of pentalogy of Cantrell, with lung extrophy.

A case of cranioraschischisis including incomplete pentalogy of Cantrell (PC) is described. The female fetus had a large omphalocele with evisceration of the heart, left lung, liver, stomach, and intestines accompanying anencephaly, cervical, thoracal lumbar, spina bifida. The fetus had ectopia cordis and diaphragmatic agenesia with an intact sternum.

Hyperthyroidism: a risk factor for female sexual dysfunction.

Introduction: Hyperthyroidism is a common hormonal disorder in women that may cause female sexual dysfunction (FSD).

Aim: To assess sexual function in women with hyperthyroidism.

Methods: A total of 40 women with clinical hyperthyroidism and 40 age-matched voluntary healthy women controls were included in the study.

Late pregnancy associated plasma protein A levels decrease in preterm labor.

Objective: The purpose of the present study is to evaluate late, 'at admission', Pregnancy-associated plasma protein-A (PAPP-A) levels as a predictor of preterm birth in women with complaints of preterm labor or preterm painful contractions.

Methods: Prospective cohort study of singleton gestations, 23-37 weeks, and symptoms of preterm labor. Primary end point was delivery < 37 weeks.

PAPP-A levels of late pregnancy in preeclampsia and HELLP syndrome.

Purpose: To determine the relationship between pregnancy-associated plasma protein-A (PAPP-A) levels and preeclampsia and HELLP syndrome at last trimester and to investigate if the severity of preeclampsia would be associated with PAPP-A levels.

Methods: Four groups were constructed; mild-preeclampsia group consisted of 19 women, severe-preeclampsia group 17, HELLP group 5 and control group 32 women. All groups were matched strictly for gestational age at last trimester.

Apgar scores in assessing morbidity of the second neonate of cephalic/non-cephalic twins in different delivery modes.

Our study was undertaken to determine whether caesarean section for the second of cephalic/non-cephalic presenting twins may prevent or diminish neonatal morbidity. For this study, 482 cephalic/non-cephalic presenting twins admitted to our hospital were retrospectively evaluated. They were separated into two groups according to their delivery mode: vaginal or caesarean delivery.

Factors affecting the accuracy of ultrasonographical fetal weight estimation in twin pregnancies.

Objective: To determine the factors affecting the accuracy of ultrasonographic weight estimation in twins.

Methods: 152 sets of twins delivered vaginally, were included. Effects of fetal weights, inter-twin weight discordance, chorionicity, early rupture of membranes, intrauterine growth restriction, and presentations of twins on errors of estimated fetal weights were evaluated.

Association of cervical infection of Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis with peritoneum colonisation in pregnancy.

This study investigated the prevalence of Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis infections in the cervices and peritoneum of pregnant women and compared them with non-pregnant controls. A total of 96 pregnant women who planned to deliver by caesarean section, and 124 non-pregnant women were screened for cervical Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis infections by polymerase chain reaction analysis. If cervical infection was present, peritoneal infection was searched from the Pouch of Douglas during caesarean section in the pregnant group and was searched by culdocentesis in the control group.

Hyperreactio luteinalis with preeclampsia.

Hyperreactio luteinalis (HL) is a condition associated with bilateral and, in rare cases, unilateral ovarian enlargement due to theca lutein cysts. HL is a benign condition, usually found incidentally at cesarean section, which can appear anaplastic and lead to unnecessary ovarian resection. A 24-year-old woman with 35 weeks of gestation attended with bilaterally enlarged ovaries.

Troponin I and homocysteine levels in mild and severe preeclampsia.

Objective: To investigate troponin I and homocysteine in pregnant women with severe and mild preeclampsia.

Methods: 43 women with mild and 22 women with severe preeclampsia, and 34 healthy pregnant women were included in the study. Homocysteine and troponin levels of the three groups were measured at admission and compared.

Sexual dysfunction in women with clinical hypothyroidism and subclinical hypothyroidism.

Introduction: Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.

Aim: To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.

Methods: A total of 25 women with clinic hypothyroidism (group 4), 25 women with subclinic hypothyroidism [thyroid stimulating hormone (TSH) value 10 mU/L (group 3)], and 20 age matched voluntary healthy women controls (group 1) were included in the study.

Prevalence of human papilloma virus infection in pregnant Turkish women compared with non-pregnant women.

Purpose Of Investigation: We aimed to find a prevalence of human papilloma virus (HPV) in order to define the 100 genotypes and subset of 14 oncogenic genotypes in pregnant Turkish women and to compare these with non-pregnant women.

Methods: Cervical thin-prep specimens were obtained from 164 women in the first trimester pregnancy and 153 non pregnant women.

Results: 29.