The effect of Farnesoid X receptor agonist tropifexor on liver damage in rats with experimental obstructive jaundice.

Purpose: To investigate experimentally the effects of Tropifexor, a farnesoid X receptor agonist, on liver injury in rats with obstructive jaundice.

Methods: Forty healthy Wistar albino female rats were divided randomly in selected groups. These groups were the sham group, control group, vehicle solution group, Ursodeoxycholic acid group and Tropifexor group.

Morphological characteristics of renal artery and kidney in rats.

The gross anatomy and morphometry of the kidney and renal arteries were studied in the strains of laboratory rat: Sprague-Dawley (Sp) and Wistar (W) rats. Total of 106 three-dimensional endocasts of the intrarenal arteries of kidney that were prepared using standard injection-corrosion techniques were examined. A single renal artery was observed in 100% of the cases.

Response of the expanded inter-premaxillary suture to intermittent compression. Early bone changes.

Objective: To determine the response of the expanded premaxillary suture in the rat to an externally applied force. Specifically, to investigate early bone changes in the expanded suture to intermittent loading and unloading.

Methods: Twenty-four 50 to 60 day-old Wistar rats were assigned to three groups.