Publications by authors named "Atilla Halil Elhan"
The incidence of asymptomatic thyroid nodules has risen enormously, with > 90% being benign. Despite limited long-term data, significant nodule growth (SNG) is common. Guidelines recommend cytology reevaluation if SNG occurs.
View Article and Find Full Text PDF: This study aimed to compare the diagnostic accuracy of the Wells and Geneva scores using a 500 ng/mL D-dimer cutoff, as well as the age-adjusted D-dimer (AADD), YEARS, and pulmonary embolism graduated D-dimer (PEGeD) algorithms, in patients with and without COVID-19. Various D-dimer cutoffs were also evaluated. This retrospective study included emergency department patients who underwent computed tomography pulmonary angiography (CTPA) for suspected pulmonary embolism (PE).
View Article and Find Full Text PDFIntroduction: Clinician burnout represents a significant occupational hazard among physicians, with a notably high prevalence among emergency physicians. The Stanford Professional Fulfillment Index (PFI) was developed to comprehensively assess various aspects of doctors' work experiences, including professional fulfillment. In this study we aimed to validate the Turkish version of the PFI (T-PFI), a 16-item instrument designed to measure physicians' professional fulfillment and burnout.
View Article and Find Full Text PDFAdenocarcinomas, a common subtype of lung cancer, exhibit diverse histological patterns. In 2020, The International Association for the Study of Lung Cancer (IASLC) introduced a grading system emphasizing high-grade components, which has shown prognostic value. Spread through air spaces (STAS) is recognized as a prognostic feature increasing the risk of recurrence in lung cancer.
View Article and Find Full Text PDFPurpose: In this study, we aimed to evaluate the response of the primary and metastatic liver tumors to radioembolization with Y glass microspheres and investigate its correlations with dosimetric variables calculated with Y PET/MRI.
Methods: In this ambispective study, 44 patients treated with Y glass microspheres and imaged with Y PET/MRI were included for analysis. Dosimetric analysis was performed for every perfused lesion using dose-volume histograms.
Purpose: To determine the accuracy of magnetic resonance imaging-proton density fat fraction (MRI-PDFF) measurements for detecting liver fat content in potential living liver donors and to compare these results using liver biopsy findings.
Methods: A total of 139 living liver donors (men/women: 83/56) who underwent MRI between January 2017 and September 2021 were included in this analysis retrospectively. The PDFFs were measured using both MR spectroscopy (MRS) and chemical shift-based MRI (CS-MRI) for each donor in a blinded manner.
Introduction: Patients with asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) have a greater disease burden than those with COPD or asthma alone. In this study, it was aimed to determine the prevalence, risk factors, and clinical features of ACO because there are limited national data in Türkiye.
Materials And Methods: The study was conducted in a cross-sectional design in nine tertiary-care hospitals.
Objectives: To evaluate adverse events (AEs) in pediatric patients with rheumatologic diseases being treated with approved or off-label biologic agents (BAs).
Methods: This observational, retrospective, multicenter study was conducted from 2010 to 2022 in patients under 18 years of age with rheumatic diseases who were receiving interleukin-1 antibodies (Anti-IL1), interleukin-6 antibodies (Anti-IL6), and tumor necrosis factor alpha inhibitors (anti-TNF). Efficacy, AEs, and timing of AEs were collected from electronic medical records.
Article Synopsis
- The study investigates the thyroid isthmus, a small middle section of the thyroid, to see if it has a higher risk of cancer than other parts of the thyroid.
- Researchers looked at data from almost 10,000 patients over several years to compare cancers found in the isthmus versus those found in the lobes of the thyroid.
- They found that while more nodules were in the lobes, a significant number of cancers were in the isthmus, but the patterns of metastasis were similar between both areas.
Article Synopsis
- This study aimed to investigate the role of human leukocyte antigens (HLA) in the recurrence and development of subacute thyroiditis (SAT) within the Turkish population, involving 51 SAT patients and 720 healthy volunteers.
- Various HLA alleles were genotyped, revealing certain subtypes significantly associated with increased risk of developing SAT and distinguishing between relapsing and non-relapsing cases.
- The findings suggest that specific HLA subtypes, including some identified as risk factors, could influence both the likelihood of SAT recurrence and its overall susceptibility in individuals.
Aims: The aim of this study was to determine the malignant potential of thyroid nodules with macrocalcifications and to evaluate the role of other sonographic findings in the diagnosis of malignancy in thyroid nodules besides macrocalcifications.
Methods: The findings of 8250 patients who applied to our outpatient clinic and underwent thyroid ultrasonography(US) between 2008 and 2021 were retrospectively reviewed. We included a total of 296 patients with 296 macrocalcified nodules (macrocalcification group) and an age- and sex matched group of 300 patients (control group) with the cytopathologic and/or histopathologic data of fine-needle aspiration biopsy (FNAB) of thyroid nodules without calcification.
In endocrine surgery, a precise ultrasonographic measurement of thyroid volume is crucial. However, there is limited comparative research between ultrasonographic and specimen volumes, which has left this issue open to debate. This study aims to assess the accuracy of recommended formulas for ultrasonographic thyroid volume measurement by comparing them to specimen volumes and analyzing the influencing variables.
View Article and Find Full Text PDFThe generalizability of artificial intelligence (AI) models is a major issue in the field of AI applications. Therefore, we aimed to overcome the generalizability problem of an AI model developed for a particular center for pneumothorax detection using a small dataset for external validation. Chest radiographs of patients diagnosed with pneumothorax (n = 648) and those without pneumothorax (n = 650) who visited the Ankara University Faculty of Medicine (AUFM; center 1) were obtained.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to create a common metric (CM) for assessing knee osteoarthritis (OA) by combining data from several frequently used scales focused on patient functioning.
- The research involved 411 patients and utilized various health assessment tools, applying the Rasch measurement model to ensure reliability and consistency across the scales.
- The resulting CM allows clinicians and researchers to easily compare and convert scores from different OA assessment scales, making evaluations more straightforward and uniform.
Article Synopsis
- - The study examines how various factors (like pathological stage and histological type) affect the likelihood of relapse in Stage I non-small cell lung cancer (NSCLC) patients after surgical treatment, with a focus on different machine-learning methods for prediction.
- - After analyzing data from 268 patients, the DeepSurv model performed best in predicting recurrence during training, while the Random Survival Forest (RSF) model excelled in the test set.
- - The findings suggest that machine-learning techniques can effectively predict NSCLC recurrence, helping doctors make informed decisions on additional treatments and follow-up care.
Objectives: This study was planned to test the reliability and validity of the Turkish version of the Pediatric Quality of Life Inventory (PedsQL) 3.0 cerebral palsy (CP) module (parent form) in children with CP.
Patients And Methods: In the validation study conducted between June 2007 and June 2009, 511 children (299 normal children, 212 children with CP) were assessed by the seven scales of PedsQL [daily activities (DA), school activities (SA), movement and balance (MB), pain and hurt (PH), fatigue (F), eating activities (EA), and speech and communication (SC)].
Objective: To investigate the significance of lumbrical muscle enhancement (LME) on magnetic resonance imaging (MRI) in rheumatoid arthritis (RA).
Materials And Methods: Blinded to the diagnoses, contrast-enhanced bilateral hand MRIs of patients with suspected early RA between 2014 and 2019 were reviewed by two observers for the presence and degree (weak/strong) of LME. The presence of other inflammatory findings was also noted.
Background: Consolidation chemotherapy strategies have demonstrated improved pathological complete response and tumor downstaging rates for patients diagnosed with rectal cancer.
Objective: This study aimed to compare perioperative outcomes and pathological complete response rates among different neoadjuvant treatment strategies in patients undergoing total mesorectal excision for locally advanced rectal cancer.
Design: Propensity score case-matched study.
Comparison of outcomes between neoadjuvant treatment followed by surgery and surgical treatment alone in patients with locally advanced esophageal cancer: Our single-center experience.
Turk Gogus Kalp Damar Cerrahisi Derg
October 2022
Article Synopsis
- This study examined the impact of neoadjuvant therapy on survival outcomes in patients with locally advanced esophageal cancer, analyzing 143 patients over a nine-year period.
- Results showed that patients who received neoadjuvant therapy had significantly higher five-year overall survival rates (52.9%) compared to those who did not receive it (8%).
- The findings suggest that neoadjuvant therapy improves both overall survival and recurrence-free survival in these patients, making it a beneficial treatment option prior to surgery.
Article Synopsis
- The study investigated the impact of the COVID-19 pandemic on the management of patients with acute appendicitis, comparing practices before and during the pandemic.
- It included a review of 8,972 patients from multiple centers to analyze differences in diagnosis, treatment approaches, and post-treatment outcomes between the pre-pandemic (Jan-Apr 2019) and pandemic (Jan-Apr 2020) periods.
- Findings showed an increase in non-operative follow-up requests and higher rates of open surgery during the pandemic, but no direct correlation was found between pandemic restrictions and the severity of acute appendicitis cases.
Objectives: Second victim experience defines the healthcare professionals involved in unexpected adverse patient events. The Second Victim Experience and Support Tool (SVEST) is a tool used to measure the second victim experience and the desired support resources. This study aims to carry out a cross-cultural adaptation of the SVEST and to evaluate the psychometric properties of the Turkish version (T-SVEST).
View Article and Find Full Text PDFObjectives: This study aims to investigate whether pulsed electromagnetic field (PEMF) therapy in addition to a conventional rehabilitation program is effective on pain and functioning in patients with type 1 complex regional pain syndrome (CRPS-1) of the hand.
Patients And Methods: Between March 2013 and January 2015, a total of 32 patients (16 males, 16 females; mean age: 50.1±13.