Publications by authors named "Atikel Y"
The genetic spectrum of polycystic kidney disease in children.
Rev Assoc Med Bras (1992)
November 2023
Article Synopsis
- The study focuses on two types of polycystic kidney disease: autosomal dominant, caused by mutations in polycystin-1 and polycystin-2, and autosomal recessive, linked to PKHD1 mutations, which results in severe kidney enlargement and liver issues.
- Researchers assessed 28 children diagnosed with polycystic kidney disease, using family history, ultrasound, and genetic analysis to confirm diagnoses.
- The genetic analysis revealed several novel variants in polycystin-1 and polycystin-2, with half being newly identified, helping to enhance clinical diagnosis and prognosis for affected children.
Article Synopsis
- The study examined how the characteristics of hospitals and dialysis units affect hospitalizations in pediatric dialysis patients, specifically for access-related complications.
- It found that children's hospitals (CHs) had more specialized staff and experience, leading to a higher use of automated peritoneal dialysis (APD) and hemodiafiltration (HDF) compared to general hospitals (GHs).
- CAPD patients faced a higher hospitalization risk due to infections, but centers with more PD experience saw lower hospitalization rates for these patients, while conventional hemodialysis (cHD) increased the risk for non-infectious complications.
First report of tethered cord syndrome in a patient with Verheij syndrome.
Ophthalmic Genet
August 2023
Background: Verheij syndrome (VRJS) is a rare microdeletion syndrome of chromosome 8q24.3 that is characterized by severe growth retardation, microcephaly, vertebral anomalies, joint laxity/dislocation, psychomotor retardation, cardiac and renal defects, and dysmorphic facial features. Pathogenic variants of PUF60 (Poly-U Binding Splicing Factor 60 kDa) have been found to cause VRJS.
View Article and Find Full Text PDFWe evaluated the demographic features, etiologic risk factors, treatment strategies, and outcome of the infants and children with urolithiasis (UL). A retrospective multicenter study was conducted including 23 Pediatric Nephrology centers in Turkey. The medical records of 2513 children with UL were reviewed.
View Article and Find Full Text PDFBackground: Nephrocalcinosis (NC) is defined as calcium deposition in the kidney parenchyma and tubules. This study aims to determine the etiology, risk factors, and follow-up results of patients with NC in Turkey.
Methods: Patients diagnosed with NC in the pediatric nephrology Department Units of 19 centers from all geographical regions of Turkey over a 10-year period (2010-2019) were included in the study.
Background/aim: Children on dialysis are under increased risk of influenza and invasive pneumococcal disease. Although vaccination against these microorganisms are recommended in dialysis patients and despite the fact that these vaccines can reduce disease burden and rates of hospitalization due to infection, vaccination rates are below expected and desired. We aimed to evaluate influenza and pneumococcal vaccination and infection rates in European pediatric dialysis centers.
View Article and Find Full Text PDFBackground: During erythropoietin-stimulating agent (ESA) treatment, hemoglobin (Hb) levels usually fluctuate; this phenomenon is known as "Hb cycling (HC)." In this study, we aimed to evaluate the predictors of HC and its impact on left ventricular hypertrophy (LVH) as a patient-important outcome parameter in pediatric dialysis patients.
Methods: Records of patients followed up in nine pediatric nephrology centers between 2008 and 2013 were reviewed.