Dynamic molecular regulation of salt stress responses in maize ( L.) seedlings.

Introduction: Maize ranks among the most essential crops globally, yet its growth and yield are significantly hindered by salt stress, posing challenges to agricultural productivity. To utilize saline-alkali soils more effectively and enrich maize germplasm resources, identifying salt-tolerant genes in maize is essential.

Methods: In this study, we used a salt-tolerant maize inbred line, SPL02, and a salt-sensitive maize inbred line, Mo17.

Genetic diversity analysis of benzimidazole resistance-associated genes in Haemonchus contortus from four regions in southern Xinjiang.

To assess the genetic diversity of the I β-tubulin haplotype gene associated with benzimidazoles (BZs) resistance in Haemonchus contortus populations across southern Xinjiang, the sampled populations from four distinct areas to detect the BZs resistance-related I-β tubulin gene and analyse its genetic sequences and structure. The results revealed substantial haplotype diversity and nucleotide polymorphisms across the four populations, with nucleotide diversity (Pi) ranging from 0.03471 to 0.

FOXO regulation of TXNIP induces ferroptosis in satellite cells by inhibiting glutathione metabolism, promoting Sarcopenia.

Aging-related sarcopenia represents a significant health concern due to its impact on the quality of life in the elderly. This study elucidates the molecular mechanisms underlying sarcopenia by employing single-cell sequencing and public transcriptome databases to compare young and aged mouse skeletal muscles. Cellular classification and pseudotime analyses differentiated cell types and their interrelationships, revealing a marked reduction in satellite cell numbers and a consistent upregulation of TXNIP (Thioredoxin interacting protein) across various muscle cell populations in aged mice.

A New Species of the Genus (Anura, Megophryidae) from Southern Hunan Province, Central China.

A new species of Asian horned toad, is described from Yongzhou City, Hunan Province, China. The species is a phylogenetically sister to based on 16S rRNA and genes. The new species differs from its congeners, possessing the following combination of characters: (1) moderate body size: SVL 37.

Long-Term Exposure to Fine Particulate Matter (PM) Components and Precocious Puberty Among School-Aged Children: Cross-Sectional Study.

Background: The increasing incidence of precocious puberty is a major health challenge for Chinese children, while related risk factors remain less well explored. Exposure to ambient fine particulate matter (PM2.5) is a leading environmental hazard in China.

PbOI: A Lead Oxyhalide IR Optical Crystal with an Unprecedented [OPb] Chain Featuring a Wide Transmittance Range and Large Birefringence.

Among the infrared (IR) optical material systems, the heavy-metal oxyhalide system has become an emerging system in recent years. Introducing heavy-metal cations and halogen anions with large atomic numbers is conducive to widening the IR transparency window and improving the birefringence value. Our experiments focus on the PbO-PbI system and find a new lead oxyhalide, PbOI.

Long-term exposure to fine particulate matter components with obesity in children and adolescents in China: The age-sex disparities and key effect modifiers.

Long-term fine particulate matter (PM) exposure was associated with childhood obesity. However, the key PM components and whether PM effect may vary by obesity type, growth stage, sex, and individual/family characteristics have yet been examined. In this study, we investigated 213,907 Chinese children and adolescents aged 3-18 years in 2017-2019.

A Patient with a Delayed Diagnosis of Zinc Powder Inhalation Poisoning: A Case Report.

Objective: Overexposure to zinc can lead to zinc poisoning. Zinc poisoning from zinc powder inhalation has rarely been reported.

Case Report: A 66-year-old male presented with nausea, chest tightness, and shortness of breath.

Constructing an Injectable Multifunctional Antibacterial Hydrogel Adhesive to Seal Complex Interfaces Post-Dental Implantation to Improve Soft Tissue Integration.

Soft tissue integration (STI) around dental implants determines their long-term success, and the key is to immediately construct a temporary soft tissue-like barrier to prevent bacterial invasion after implantation and then, promote STI. In response to this need, an injectable multi-crosslinked hydrogel (MCH) with abilities of self-healing, anti-swelling, degradability, and dry/wet adhesion to soft tissue/titanium is developed using gallic acid-graft-chitosan, oxidized sodium alginate, gelatin, and Cu with water and borax solution as solvents, whose properties can be controlled by adjusting its composition and ratio. MCH can not only immediately build a sealing barrier to block the bacterial invasion in the oral simulation environment but also deliver outstanding antibacterial efficacy through the synergism of trapping bacteria and releasing bactericidal agents such as chitosan, gallic acid, aldehyde, and Cu.

3PbOI·2CsI: the salt-inclusion strategy enriches the structural chemistry in lead oxyhalides.

The design and synthesis of new mid-infrared functional crystals with novel structures and excellent properties is a hot topic in the materials science research field. Different from the traditional mid-far infrared crystal systems, such as chalcogenides and phosphides, a recently developed heavy metal oxyhalide, with a wide bandgap and transmittance range, is a very promising mid-infrared crystal material research system. Herein, the first case of a salt-inclusion compound in lead oxyhalides, CsPbOI (3PbOI·2CsI), has been synthesized by a high-temperature solution method.

The Effect of Infiltration Temperature on the Microstructure and Magnetic Levitation Force of Single-Domain YBaCuO Bulk Superconductors Grown by a Modified Y+011 IG Method.

During the preparation of single-domain (S-D) REBaCuO (RE-123) superconducting bulks, the seed crystals can serve as templates for crystal growth, guiding the newly formed crystals to grow in a specific direction, thereby ensuring the consistency of the crystal orientation within the sample. However, the infiltration temperature is typically restricted to approximately 1050 °C when employing NdBaCuO (Nd-123) crystal seeds in the traditional top-seeded infiltration growth (TSIG) technique for producing single-domain Y-123 bulk superconductors. In the present study, to overcome the temperature limitations of the heat treatment process, the optimized YO +011 IG (011 refers to BaCuO powder) method was employed to fabricate a group of single-domain Y-123 bulks with a high-temperature infiltration (1000-1300 °C).

Gaps in knowledge and management of iron deficiency in heart failure: a nationwide survey of cardiologists in China.

Background: Heart failure (HF) guidelines recommend routine testing for iron deficiency (ID) and, for those with ID, intravenous iron if the left ventricular ejection fraction is <50%. Guideline adherence to these recommendations by cardiologists in China is unknown.

Methods And Results: An independent academic web-based survey was designed and distributed via social networks to cardiologists across China.

First report of the whole‑genome sequence analysis of Fig badnavirus 2 from China.

A novel plant virus was identified in fig trees exhibiting ring spot symptoms through high-throughput sequencing (HTS). The complete genome sequence was successfully determined using PCR and RT-PCR techniques. The virus features a circular DNA genome of 7233 nucleotides (nt) in length, encompassing four open reading frames (ORFs).

A Novel Differentiation Nomogram Model for Brucellar Spondylitis and Tuberculous Spondylitis.

Background: Tuberculous spondylitis (TS) and brucellar spondylitis (BS) exhibit certain similarities in clinical presentation and imaging characteristics, making differential diagnosis challenging. Developing a reliable differential diagnosis model can assist clinicians in distinguishing between these two conditions at an early stage, allowing for targeted prevention and treatment strategies.

Methods: Patients diagnosed with TS and BS were retrospectively collected and randomized into training and validation cohorts (ratio 7:3).

Insight into the history and trends of liver transplantation for echinococcosis: A bibliometric analysis.

Background: Liver transplantation (LT) has demonstrated favorable efficacy in managing end-stage alveolar echinococcosis. Nevertheless, the current research focal points and advancement trends remain ambiguous.

Aim: To map the research landscape to underscore critical areas of focus, influential studies, and future directions of LT for echinococcosis treatment.

Analysis of risk factors for surgical site infection in spinal surgery patients and study of direct economic losses.

Background: Surgical site infection (SSI) is a serious complication of spine surgery, leading to prolonged hospital stays, re-operations, and economic losses. The aim of the study was to explore the types and quantities of pathogenic bacteria involved, the incidence of SSI, and to identify the independent risk factors and direct economic impact on patients with postoperative SSI in spine surgery.

Methods: The medical records of spine surgery patients from January 2023 to April 2024 at two hospitals in Xinjiang were retrospectively reviewed.

Shared genetic architecture and bidirectional clinical risks within the psycho-metabolic nexus.

Background: Increasing evidence suggests a complex interplay between psychiatric disorders and metabolic dysregulations. However, most research has been limited to specific disorder pairs, leaving a significant gap in our understanding of the broader psycho-metabolic nexus.

Methods: This study leveraged large-scale cohort data and genome-wide association study (GWAS) summary statistics, covering 8 common psychiatric disorders and 43 metabolic traits.

AI-driven eyelid tumor classification in ocular oncology using proteomic data.

Eyelid tumors pose diagnostic challenges due to their diverse pathological types and limited biopsy materials. This study aimed to develop an artificial intelligence (AI) diagnostic system for accurate classification of eyelid tumors. Utilizing mass spectrometry-based proteomics, we analyzed proteomic data from eight tissue types and identified eighteen novel biomarkers based on 233 formalin-fixed, paraffin-embedded (FFPE) samples from 150 patients.

Exploring the Microbial Landscape of Bone and Joint Infections: An Analysis Using 16S rRNA Metagenome Sequencing.

Background: Bone and joint infections (BJIs) are challenging to diagnose. This study evaluated the utility of 16S rRNA gene sequencing in diagnosing BJIs, comparing it with conventional bacterial culture to explore microbial diversity in orthopedic infections.

Methods: Thirty patients with BJIs were enrolled from January 2019 to September 2020 at a single orthopedic center.

Analytical Performance of a Novel Nanopore Sequencing for SARS-CoV-2 Genomic Surveillance.

The genomic analysis of SARS-CoV-2 has served as a crucial tool for generating invaluable data that fulfils both epidemiological and clinical necessities. Long-read sequencing technology (e.g.

Transcriptome-based characterization of 3'2'-cGAMP signaling mediated immune responses.

Cyclic dinucleotides (CDNs) are critical adjuvants in antiviral vaccines and cancer immunotherapy, primarily through the activation of the cGAS-STING signaling pathway. Evaluating the immune responses triggered by CDNs is essential for the development of effective adjuvants. In this study, we performed a comparative transcriptome analysis to characterize the immune responses elicited by the recently identified nuclease-resistant Drosophila and bacterial CDN, 3'2'-cGAMP, in mammalian immune cells.

Upregulation of CRISP3 and its clinical values in adult sepsis: a comprehensive analysis based on microarrays and a two-retrospective-cohort study.

Background: Current lines of evidence indicate that cysteine-rich secretory protein 3 (CRISP3) is an immunoregulatory factor. Nevertheless, no study has explored the relationships between the values of CRISP3 and sepsis.

Methods: We conducted a comprehensive literature search and meta-analysis from the Gene Expression Omnibus (GEO) and ArrayExpress to determine the expression of CRISP3 in sepsis patients.

Diabetic Cardiomyopathy Uncovered: Transcriptomics, NLRP3, and Carvedilol Mechanisms.

This study investigates the impact of a high-sugar environment on H9C2 cardiomyocytes and explores the protective effects of carvedilol in the context of diabetic cardiomyopathy (Dia-CM). Transcriptomic analysis identified 21,655 differentially expressed genes associated with Dia-CM, demonstrating significant separation among samples. H9C2 cardiomyocytes were cultured in a high-sugar environment to simulate Dia-CM conditions.

Management of large or giant Extracranial carotid artery aneurysms: a single-center experience.

Background: Extracranial carotid artery aneurysm (ECCA) is an infrequent disease with an incidence of less than 1%. However, our understanding is still incomplete, and the preferred method to treat ECAA remains unknown.

Methods: To share our initial experience with treatment options for large ECCAs.