Publications by authors named "Atija Kapidzic"

Article Synopsis
  • - The study compared the effectiveness of one sample FIT (1-FIT) versus two sample FIT (2-FIT) screenings for colorectal cancer over four rounds, focusing on participation, positive predictive value, and diagnostic yield.
  • - A population-based sample of asymptomatic individuals aged 50-74 in the Netherlands was invited to participate, with data collected from those who completed at least one round of screening over a nine-year period.
  • - Results showed that participation rates were slightly higher for 1-FIT (74.7%) compared to 2-FIT (72.5%), indicating a preference for the single sample test among invitees.
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Several studies suggest that test characteristics for the fecal immunochemical test (FIT) differ by gender, triggering a debate on whether men and women should be screened differently. We used the microsimulation model MISCAN-Colon to evaluate whether screening stratified by gender is cost-effective. We estimated gender-specific FIT characteristics based on first-round positivity and detection rates observed in a FIT screening pilot (CORERO-1).

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Article Synopsis
  • The study compared the effectiveness of 1-sample and 2-sample faecal immunochemical testing (FIT) for colorectal cancer screening over two rounds among average-risk subjects aged 50-74 years.
  • The attendance rates for both types of screenings were similar, but the positivity rate was higher for the 2-sample FIT during the second round.
  • Ultimately, both screening methods had comparable detection rates for advanced neoplasia, suggesting that 1-sample FIT may be the preferred option without sacrificing diagnostic yield.
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Objectives: Fecal immunochemical testing (FIT) and colonoscopy are tandem procedures in colorectal cancer (CRC) screening. A positive FIT predicts advanced neoplasia (AN) that requires endoscopic detection and removal. En bloc or piecemeal resection of AN is associated with a significant rate of residual or recurrent neoplasia.

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Background & Aims: Fecal immunochemical tests (FITs) are used widely in colorectal cancer screening. Programs use the same fecal hemoglobin threshold for colonoscopy referral for men and women, but it is unclear whether FIT performs equally in both sexes. We therefore assessed FIT performance in men and women.

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Objectives: Fecal immunochemical test (FIT) screening for colorectal cancer (CRC) requires timely successive rounds for an optimal preventive effect. However, data on attendance and trend in yield over multiple rounds of FIT screening are limited. We therefore conducted a consecutive third round of FIT screening in a population-based CRC screening trial.

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