Background: Incidence of hypokalemia during the management of diabetic ketoacidosis (DKA) is high despite detailed potassium replacement guidelines in its treatment.
Aim: We aimed to find the role of pH-adjusted potassium (pH ) in the development of hypokalemia, and their mutual impact on patient outcomes during DKA management.
Methodology: Adult DKA patient's admission data of preceding 3 years (2015-2017) were retrospectively clerked.
Background And Aims: Diabetic ketoacidosis (DKA) treatment guidelines recommend to initiate potassium-replacement when serum potassium (S) drops within normal range, and to withhold insulin if S is below normal. Despite strict recommendations, hypokalemia is frequently observed in DKA.
Methods: Scientific literature was thoroughly searched to find 1) DKA treatment guidelines, 2) studies reporting hypokalemia in DKA, 3) and literature elaborating mechanisms involved in hypokalemia.
Ethnopharmacological Relevance: Bougainvillea glabra (Choisy). (Family: Nyctinaginacea) is a valuable ornamental plant with culinary uses and also utilized in traditional medicine for treating common ailments. It is traditionally employed against several diseases such as diarrhoea, hypotension, intestinal disorders, stomachache, nausea, inflammation-related ailments, and in pain management.
View Article and Find Full Text PDFBackground: During the progress and resolution of a diabetic ketoacidosis (DKA) episode, potassium levels are significantly affected by the extent of acidosis. However, none of the current guidelines take into account acidosis during resuscitation of potassium level in DKA management, which may increase the risk of cardiovascular adverse events.
Objective: To assess literature regarding the adjustment of potassium level using pH to calculate pH-adjusted corrected potassium level, and to observe the relationship of cardiovascular outcomes with reported potassium level and pH-adjusted corrected potassium in DKA.
Front Endocrinol (Lausanne)
March 2018