Publications by authors named "Athiyamaan M"
Article Synopsis
- Cervical cancer affects around 600,000 women globally each year, and this study focused on how treatment timing, specifically the gap between external beam radiotherapy and brachytherapy, impacts early recurrences.
- Data was collected from medical records of 288 cervical cancer patients, revealing that 93% had a complete response to treatment yet 8% experienced early cancer recurrences within six months.
- The research found a significant correlation between longer overall treatment times and increased risk of early recurrences, suggesting that optimizing treatment schedules could improve patient outcomes.
There has been growing interest in the use of epidermal growth factor receptor inhibitors in various cancers. The study was conducted to evaluate the efficacy and safety of gefitinib as a monotherapy in patients with recurrent or metastatic cervical cancer. Patients with cervical carcinoma who experienced locoregional recurrence or distant metastases either at presentation or after definitive combined chemoradiotherapy or postoperative radiotherapy were enrolled.
View Article and Find Full Text PDFBackground: To develop a dosimetric tool to estimate the dose delivered in the presence of air pockets with EBT3 film while simulating the conditions of vaginal vault brachytherapy (VVBT) with 3.0 diameter cylindrical applicator at a prescription dose distance of 5mm from the surface of it.
Materials And Method: Six acrylic plates (10 cm x 10 cm, 0.
Aim: To determine the effect of cochlear dose on sensorineural hearing loss in patients with head and neck cancer treated by radiotherapy and chemoradiotherapy.
Materials And Method: A two-year longitudinal study was conducted on 130 subjects with various head and neck malignancies who were receiving radiotherapy or chemoradiation. 56 patients received only radiotherapy while 74 patients received concurrent chemoradiation five days a week at a dose of 66-70 Gy.
Background: To assess and compare the local control and toxicities between HDR Intracavitary Brachytherapy with 7.5 Gy and 9 Gy per fraction after EBRT in treatment of carcinoma cervix.
Methodology: A total of 180 patients were randomly assigned to 2 arms.
Background: A semiconductor rectal probe was used to compare planned and measured rectal doses during Co-60 high dose rate (HDR) CT-based intracavitary brachytherapy applications (ICBT) of cervical cancer.
Materials And Methods: A total of 22 HDR brachytherapy applications were included from 11 patients who were first treated with EBRT to the whole pelvis with a total prescribed dose of 50 Gy in 25 fractions. During each application, a PTW 9112 probe rectal probe having a series of five semiconductor diodes (R1 to R5) was inserted into the patient's rectum and a CT-based HDR ICBT application with a prescribed dose per fraction of 7 or 7.
Background: Aim of this study is to evaluate the efficacy of inhomogeneity corrections calculated by radiotherapy treatment planning system (TPS) using various densities of materials.
Materials And Methods: Gammex Computed tomography electron density inserts (EDI's; 14 no's) were used to generate the CT to ED curve with high speed GE CT scanner by noting down the respective HU values of each rod. Treatment plans were generated in XiO TPS with three inhomogeneous phantoms (comprising combination of water, lung and bone equivalent slabs) with different field sizes and for EDI (8 no's) inserted in slots of acrylic tray and validation was carried out using 2D array detector with 20cm×20cm field size for 200 MU.
Background: The aim of this study is to design and fabricate a thorax phantom with irregularly shaped trapezoidal slots across the left side of the chest wall, allowing for the creation of unwanted air gaps under the bolus.
Method: Surface dose (Dsurf) measurements were made with Gaf Chromic EBT3 films at air gaps (0.0, 5.
Aim: A tissue-equivalent bolus of sufficient thickness is used to overcome build up effect to the chest wall region of postmastectomy radiotherapy (PMRT) patients with tangential technique till Radiation Therapy Oncology Group (RTOG) Grade 2 (dry desquamation) skin reaction is observed. The aim of this study is to optimize surface dose delivered to chest wall in three-dimensional radiotherapy using EBT3 film.
Materials And Methods: Measurements were conducted with calibrated EBT3 films with thorax phantom under "open beam, Superflab gel (0.