Publications by authors named "Atharva Mahale"
Article Synopsis
- High-grade gliomas (HGGs) are aggressive brain tumors with high mortality, and there's a need for better treatment options despite some research progress.
- This study utilized targeted proteomics and molecular docking combined with drug repurposing to find potential new drug candidates for treating HGGs, focusing on specific proteins involved in tumor development.
- Promising drugs like Pazopanib showed increased effectiveness when used with Temozolomide, highlighting potential new treatment strategies, but further clinical trials are necessary to confirm these findings.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an RNA virus possessing a spike (S) protein that facilitates the entry of the virus into human cells. The emergence of highly transmissible and fit SARS-CoV-2 variants has been driven by the positive selection of mutations within the S-protein. Notable among these variants are alpha, beta, gamma, delta, and omicron (BA.
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