Publications by authors named "Athanassios Sinaniotis"

Article Synopsis
  • The study aims to understand why peanut allergy (PA) severity differs among patients by analyzing data from 393 cases, focusing on clinical profiles and predictive factors for severity.* -
  • Results indicate that factors such as female sex, age of onset, and specific allergies (e.g., atopic dermatitis, latex) are linked to more severe PA, while birch pollen allergy is associated with milder cases.* -
  • Although some IgE levels (like those to peanut extract and specific components) correlate with PA severity, clinical background factors remain the most effective predictors of an individual patient's risk for severe allergic reactions.*
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Allergy to banana fruit appears to have become an important cause of fruit allergy in Europe. Among five allergens that have been found, beta-1,3-glucanase denoted as Mus a 5 was identified as a candidate allergen for the component-resolved allergy diagnosis of banana allergy. Because of the variations in protein levels in banana fruit, in this study Mus a 5 was produced as a fusion protein with glutathione-S-transferase in Escherichia coli.

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Scope: Banana fruit has become an important cause of fruit allergy in the recent years. Among the five registered IUIS allergens, Mus a 1 and Mus a 2 have been characterized in detail. In this study, molecular characterization and evaluation of the allergenic properties of β-1,3-glucanase from banana (Musa acuminata), denoted as Mus a 5, were performed.

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Background: European legislators and wine producers still debate on the requirement for labeling of wines fined with potentially allergenic food proteins (casein, egg white or fish-derived isinglass). We investigated whether wines fined with known concentrations of these proteins have the potential to provoke clinical allergic reactions in relevant patients.

Methods: In-house wines were produced for the study, fined with different concentrations of casein (n = 7), egg albumin (n = 1) and isinglass (n = 3).

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Purpose Of Review: This review highlights recent developments in the diagnosis, etiology, therapy, and prevention of community-acquired pneumonia in children.

Recent Findings: Sensitive new diagnostic methods have increased the detection rate of the causative agent up to 94%. Streptococcus pneumoniae is the most prevalent bacterial pathogen in all ages.

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