Publications by authors named "Athanassios N Manginas"
Article Synopsis
- Pulmonary arterial hypertension (PAH) is a serious condition affecting small pulmonary arteries, causing increased resistance, which can lead to right heart failure and potentially death.* -
- While specific drug treatments have improved survival rates for PAH patients, complications like pulmonary artery dilatation and sudden cardiac events still pose significant risks.* -
- Referral centers for PAH provide specialized emergency care and management, enhancing patient quality of life and survival, despite the need for quick decision-making regarding severe complications and potential lung transplantation.*
Pulmonary arterial hypertension is a rare and devastating disease characterized by vascular proliferation and remodeling. Epoprostenol, the drug counterpart of the eicosanoid prostacyclin, produced by the vascular endothelial cells, is the drug of choice for this disease. Its capacity to act rapidly and to significantly improve survival prospects in severe pulmonary hypertension patients has been supported by a wealth of evidence.
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