Publications by authors named "Athanasios Papadis"

Objective: Transcatheter Aortic Valve Implantation (TAVI) has emerged as a pivotal therapeutic modality for aortic stenosis, predominantly in the elderly population. Despite its clinical success, the incidence and implications of vascular complications during TAVI remain a subject of critical concern.

Methods: A retrospective analysis was conducted on 140 patients who experienced vascular complications during TAVI procedures from a total cohort of 1343 cases.

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Background: Pericardial effusion (PE) is the most common serious left atrial appendage closure (LAAC) complication, but its mechanisms, time course, and prognostic impact are poorly understood.

Objectives: This study sought to assess the frequency, timing, predictors and clinical impact of PE after LAAC.

Methods: Data on consecutive patients undergoing percutaneous LAAC between 2009 and 2022 were prospectively collected including the 1-year follow-up.

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Article Synopsis
  • The study focused on evaluating the reliability of measuring aortic valve area (AVA) using 3D transesophageal echocardiography compared to other methods, specifically the continuity equation (CE).
  • It involved 119 patients with varying severity of aortic stenosis and utilized different approaches: the standard CE, a modified CE using 3D reconstruction, and direct 3D measurement.
  • Results showed that while the 3D measurements (AVA-3D) were significantly higher than standard and modified CE methods, in patients with smaller AVAs, the differences were negligible, indicating that the new method aligns well with traditional measurements and is reliable for clinical use.
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Background: According to current guidelines, hemodynamic status should guide the decision between immediate and delayed coronary angiography (CAG) in out-of-hospital cardiac arrest (OHCA) patients without ST-segment elevation. A delayed strategy is advised in hemodynamically stable patients, and an immediate approach is recommended in unstable patients.

Objectives: This study sought to assess the frequency, predictors, and clinical impact of acute coronary occlusion in hemodynamically stable and unstable OHCA patients without ST-segment elevation.

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Article Synopsis
  • - The study examines how the flow of blood (Q) relates to the area of the aortic valve opening (AVA) through different echocardiographic stress tests, particularly low-dose dobutamine stress echocardiography (DSE), to distinguish between pseudo-severe and true severe aortic stenosis.
  • - Three progressively intense stress maneuvers (passive leg raise, maximal dobutamine infusion, and their combination) were tested on 45 patients, revealing that while Q increased significantly, AVA showed signs of saturation, evidenced by a decrease in AVA and valve compliance.
  • - The analysis indicated that the relationship between Q and AVA conforms more closely to a saturating model rather than a linear one
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The new outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has an impact worldwide, primarily as a medical emergency. Even that the total constellation is considered as a pandemic of acute respiratory disease, coronavirus disease 2019 (COVID-19) gives rise to dysfunction in multiple organs (e.g.

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Background: Dobutamine stress echocardiography is used to increase transvalvular flow in patients with low-flow, low-gradient aortic stenosis (AS). Dobutamine fails to increase the stroke volume index (SVI) in one third of patients. The aim of this study was to test whether passive leg raise (PLR) added to dobutamine could increase SVI and transvalvular flow in patients with severe paradoxical low-flow, low-gradient AS.

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Background: Up to 70% of out-of-hospital cardiac arrest (OHCA) patients have a relevant coronary stenosis which may need revascularization. The short- and long-term ischemic and bleeding risk of unconscious and conscious OHCA patients undergoing percutaneous coronary intervention (PCI) is largely unknown.

Objectives: This study sought to compare the occurrence of 1-year outcomes after PCI between OHCA patients, stratified on the basis of state of consciousness, with patients with acute coronary syndrome (ACS) not preceded by OHCA.

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Background: Rheumatic heart disease (RHD) accounts for the highest number of deaths from valvular heart disease globally. Yet, rheumatic aortic stenosis (AS) was excluded from landmark studies investigating the safety and efficacy of transcatheter aortic valve implantation (TAVI). We aimed to describe the clinical and anatomical characteristics of patients with rheumatic AS undergoing TAVI, and to compare procedural and clinical outcomes with patients undergoing TAVI for degenerative AS.

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The interconnections between brain and heart are increasingly recognized. Takotsubo cardiomyopathy, also known as "broken heart syndrome", is characterized by a cardiovascular dysfunction provoked by an emotional or stressful situation. Similar events can trigger a neurological pathology called transient global amnesia.

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Introduction: The electrocardiogram (ECG) is a valuable diagnostic tool for the diagnosis of myocardial ischemia during acute coronary syndrome. Aside from the commonly used ST-segment shift indicative of ischemia, several other ECG parameters are pathophysiologically reasonable. Thus, the goal of this study was to assess the accuracy of different ischemia parameters as obtained by the highly susceptible intracoronary ECG (icECG).

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