Publications by authors named "Atefeh Yaghoubi"
An overview of post transplantation events of decellularized scaffolds.
Transpl Immunol
October 2022
Article Synopsis
- Regenerative medicine and tissue engineering offer potential alternatives to organ transplantation by using decellularized tissues for repairing damaged tissues.
- The decellularization process retains key components of the extracellular matrix, creating 3D scaffolds that possess favorable mechanical properties and biocompatibility.
- The review addresses post-transplantation events like cell migration, blood vessel formation (angiogenesis), and interactions with immune cells in decellularized scaffolds.
Introduction: Regenerative medicine provides promising approaches for treating chronic liver diseases. Previous studies indicate that decellularized liver architecture is damaged by invading non-hepatic inflammatory cells. This study aimed to use anti-inflammatory and regenerative potency of bone marrow-derived mesenchymal stem cells (BM-MSC) and prednisolone for reducing fibrosis and balancing inflammatory cell migration into the decellularized liver scaffold.
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