Signature of an early genetic bottleneck in a population of Moroccan sardines (Sardina pilchardus).

Fishery assessment models meant to determine sustainability of commercial marine fish failed to predict recent stock collapses due to overexploitation. One flaw of assessment models is that they strongly rely on catch and age-composition statistics, but largely ignore the genetic background of the studied populations. We examined population genetic structure of sardine (Sardina pilchardus) in the centraleastern and northeastern Atlantic Ocean and Mediterranean Sea to aid fishery management of this heavily fished small pelagic species.

Identification of two highly performing Leishmania infantum antigens for serodiagnosis of canine leishmaniosis.

In the aim of improving serodiagnosis of canine leishmaniosis, we analysed the humoral immune response of dog against Leishmania infantum parasite. The antigenic reaction of L. infantum polypeptides with sera from 31 dogs with parasitologically confirmed leishmaniosis was studied by using the immunoblot technique.

Camel trypanosomosis in Morocco. 2. A pilot disease control trial.

A first epidemiological study on camel trypanosomosis was conducted in 1997 and 1998 in five Moroccan Saharan provinces. It revealed two major foci at Merzouga (Tafilalet province) and Zagora (Ouarzazate province) where tour camel seroprevalences were 35.4 and 43.

[Canine leishmaniasis in the Rif mountains (Moroccan Mediterranean coast): a seroepidemiological survey].

A sero-epidemiological survey has been conducted in several localities of the province of Nador to investigate canine leishmaniasis in the North-Eastern slope of the Rif mountains (Mediterranean coast of Morocco). Serum samples collected from 257 dogs were analysed using indirect fluorescent antibody test (IFAT) and enzyme-linked immunosorbent assay (ELISA) to detect anti-Leishmania infantum antibodies. Forty eight (18.

Camel trypanosomosis in Morocco 1: results of a first epidemiological survey.

An epidemiological survey of camel trypanosomosis was conducted for the first time in Morocco in 1997 and 1998. Five provinces located in the south and southeast of the High Atlas mountain chain were included in this study. A total number of 1460 serum samples were collected and tested by a card agglutination test for trypanosomosis (CATT) and enzyme-linked immunosorbant assay (Ab-ELISA) to detect anti-Trypanosoma evansi antibodies.

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains.

We cloned 17 different PCR fragments encoding VH genes of camel (Camelus dromedarius). These clones were derived from the camel heavy chain immunoglobulins lacking the light chain counterpart of normal immunoglobulins. Insight into the camel VH sequences and structure may help the development of single domain antibodies.

Naturally occurring antibodies devoid of light chains.

Random association of VL and VH repertoires contributes considerably to antibody diversity. The diversity and the affinity are then increased by hypermutation in B cells located in germinal centres. Except in the case of 'heavy chain' disease, naturally occurring heavy-chain antibodies have not been described, although antigen binding has been demonstrated for separated heavy chains or cloned VH domains.