A distinctive and proficient fluorescent switch for ratiometric recognition of the menacing cyanide ion: biological studies on MDA-MB-231 cells.

A new fluorescent ratiometric switch (BOHB) was developed for swift and selective detection of cyanide ions in aqueous media without any interference from other competitive anions. Upon gradual addition of cyanide ions into the probe solution, a prominent fluorescence color change from yellow to cyan was observed under a UV chamber. The fluorescence changes thus observed were ratiometric, and the detection limit of this new probe was found to be (22.

Efficient solid- and solution-state emissive reusable solvatochromic fluorophores for colorimetric and fluorometric detection of CN.

In this work, a novel organic receptor, CPI [()-3-(4-(9-carbazol-9-yl)phenyl)-2-(1-benzo[]imidazol-2-yl)acrylonitrile], was rationally designed and successfully fabricated for selective and sole recognition of CN ions over other competitive anions through an obvious chromogenic and ratiometric emission change in DMSO. The distinct and prominent color change upon the addition of CN can be attributed to the typical ICT process, which is induced by the deprotonation of acidic NH protons in the imidazole moiety. The sensor displayed strong solvatochromic effects in commonly used organic solvents such as -hexane, toluene, diethyl ether, DCM, THF, DMF and DMSO.

A chemodosimetric approach for the visual detection of nerve agent simulant diethyl chlorophosphate (DCP) in liquid and vapour phase.

In this work, a novel fluorescent ratiometric switch, 8-((6-(1-benzo[]imidazol-2-yl)pyridin-2-yl)methoxy)quinoline (BIPQ), has been introduced for sensing an organophosphorus (OP) chemical vapor threat, diethyl chlorophosphate (DCP), the low-toxic mimic of the real nerve agent sarin (GB). BIPQ is efficient at detecting DCP in both solution and gaseous phase and has potential practical application with high sensitivity and selectivity. The probe shows significant ratiometric emission in the presence of DCP along with a distinct color change from blue to cyan under UV light.

A biphenyl thiosemicarbazide based fluorogenic chemosensor for selective recognition of Cd: application in cell bioimaging.

A diversified biphenyl thiosemicarbazide based chemosensor (HBMC) has been fabricated and reported for the specific detection of Cd in a MeOH : HO (4 : 1) solution. We observed a chromogenic change from colorless to light yellow colour, and it showed a "turn-on" fluorogenic change from non fluorescent to blooming cyan colour. In fluorometric titration a sharp "turn-on" emission for Cd was observed with a ∼16 fold increase in fluorescence intensity value at 496 nm by incremental addition of Cd ions in the MeOH : HO (4 : 1) solution.