The linear allometric relationship between total metabolic energy per life span and body mass of mammals.

The aim of this study is to establish and calculate the exact allometric relationship between the total metabolic energy per life span and the body mass in a wide range of mammals with about six orders of magnitude variation of the body mass of animals. The study shows that it exists a linear relationship between the total metabolic energy per life span PT(ls) (kJ) and the body mass M (kg) of 95 mammals (3 monotremes, Subclass Prototheria, 16 marsupialis (Subclass Theria, Infraclass Metatheria) and 76 placentals (Subclass Theria, Infraclass Eutheria)) from type: PT(ls)=A(ls)(+)M(1.0511), where P (kJ/day) is the basal rate of metabolism and T(ls) (days) is the mean life span of animals.

The linear alometric relationship between total metabolic energy per life span and body mass of poikilothermic animals.

A linear relationship exists between total metabolic energy per life span PT(ls) (kJ) and body mass M (kg) of 54 poikilothermic species (Protozoa, Nematoda, Mollusca, Asteroidae, Insecta, Arachnoidae, Crustacea, Pisces, Amphibia, Reptilia and Snakes): PT(ls) = A(ls*)M(1.0838), where P (kJ/day) is the rate of metabolism and T(ls) (days) is the life span of animals. The linear coefficient A(ls*) = 3.

Nasal and sleep cycle--possible synchronization during night sleep.

Regular cyclic changes in nostril airflow due to a nasal congestion and decongestion are known in literature as nasal cycle. Registration of breathing from each nostril separately gives possibility to registrate moments of alternative change of airflow of nostrils and periods of nasal cycle. This registration during night sleep shows that the length of these periods are about 1.

Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation.

A fraction from crude extract of Galega officinalis L. was purified by gel filtration on Sephadex G-25, Sepharose 4B, and ion-exchange chromatography on diethylaminoethyl (DEAE)-cellulose. The fraction with molecular weight 100-140 kDa appears to have a polysaccharide nature, including protein.

Nitroxyl radicals and malignant pigment melanoma.

Our studies showed that the spin-labeled (SL) compounds (free stable nitroxyl radical derivatives) accumulate predominantly in pigment melanoma and some of them possess high antimelanoma activity (100% curability of tumor bearing animals) and lower general toxicity. Taking into account our results we describe a proposed mechanism of the spin-labeled accumulation in melanoma, their antimelanoma activity and lower toxicity.