Objectives: Children with congenital tracheal stenosis born in the developing world face a high risk of mortality due to limited access to proper treatment. Patients who required preoperative respiratory support were suspected to have poor survival after slide tracheoplasty; however, this was not clearly demonstrated in the previous studies. This study aims to investigate the impact of preoperative respiratory conditions on outcomes of slide tracheoplasty.
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March 2024
Persistent diarrhea is a severe gastroenteric disease with relatively high risk of pediatric mortality in developing countries. We conducted a randomized, double-blind, controlled clinical trial to evaluate the efficacy of liquid-form Bacillus clausii spore probiotics (LiveSpo CLAUSY; 2 billion CFU/5 mL ampoule) at high dosages of 4-6 ampoules a day in supporting treatment of children with persistent diarrhea. Our findings showed that B.
View Article and Find Full Text PDFIntroduction: With increased diagnostic capabilities and treatment modalities in the field of primary immunodeficiencies (PID), many pediatric patients survive beyond childhood and experience a change of care to the adult-oriented healthcare system. Unfortunately, the transition pathways for PID are less clearly defined, resulting in deterioration of quality of care in adulthood. Hence, this is the first regional study to address PID clinicians' opinions on practices and challenges of transition care in 7 Southeast Asia (SEA) countries.
View Article and Find Full Text PDFThis research examined the interplay among personal factors, namely channel lock-in, cross-channel synergy, attribute-based decision making (ADM); environmental factors, namely others' past switching behaviour (OPB), pressure to switch from others (PSO); and behavioural factors, namely perceived self-efficacy and perception on facilitating conditions as antecedents to customers' channel switching intention in an omnichannel context. Drawing on the complexity theory and set theory, we applied configurational analysis using the fuzzy-set Qualitative Comparative Analysis. The result of the analysis indicated two (2) sufficient configurations that led to an intention to switch channels.
View Article and Find Full Text PDFHum Immunol
March 2023
Several studies have reported an association between certain human leukocyte antigen (HLA) alleles and carbamazepine (CBZ)-induced hypersensitivity reactions in patients with epilepsy. Here, the relationship between the clinical spectrum and the HLA allele profiles in patients with CBZ-induced hypersensitivity reactions was investigated using next-generation sequence (NGS) data obtained from 65 Vietnamese patients with epilepsy, including 33 with CBZ-tolerance and 32 patients with CBZ-hypersensitivity, in which only 8 with severe cutaneous adverse drug reactions and 24 were mild-hypersensitive patients. Three loci of HLA class I (HLA-A, -B, and -C) and two loci of HLA class II (HLA-DQA1 and -DRB1) were included in our analysis.
View Article and Find Full Text PDFObjective: Measles is still common in many developing countries, and its outbreaks have been on the rise since 2009 even though the disease is almost entirely preventable through safe and effective vaccination. This paper aims to provide evidence about the systematic review of the cost-effectiveness of measles treatment in different regions worldwide.
Methods: The methodical search began on 10th January 2019 to look for all articles on the cost-effectiveness of measles treatment published from January 2019 to April 2019 in SCOPUS, Pubmed (www.
In this work, mesoporous TiWO₂ materials with high conductivity and surface area as promising catalyst support for Pt in Proton-Exchange Membrane Fuel Cells (PEMFCs) were synthesized via a single-step solvothermal process at low-temperature without using any surfactants or stabilizers. The characterizations of material are measured via XRD, TEM, SEM-EDS, and BET as well as electronic conductivity measurement. As a result, TiWO₂ formed a homogenous solid solution with mesoporous anatase-TiO₂ structure and uniformly spherical nanoparticles morphology of about ~10 nm diameter, together with a high electrical conductivity of 0.
View Article and Find Full Text PDFThe degradation of Pt-based catalysts is considered as the main barrier to the commercialization of fuel cells. M-doped TiO2 (M is a transition metal) has been investigated to improve the stability of electrocatalysts. Recently, W-doped TiO2 materials have been found as a good catalyst support for the photocatalyst applications but their application in Proton-exchange membrane fuel cell application has rarely been reported.
View Article and Find Full Text PDFNon-carbon materials are considered as the promising candidates for carbon-based catalyst support to increase the durability of proton exchange membrane fuel cells (PEMFCs). Due to the high stability and good electrical conductivity of TiO2, M-doped TiO2 (M is transition metals: Mo, Ru, V, W) is an emerging candidate for Pt nanoparticles support on the cathode side of PEMFCs. In this research, the synthesis mechanism of Ti0.
View Article and Find Full Text PDFIn this paper, Fe@SiO2 nanoparticles (α-Fe nanoparticles coated with SiO2 shell) were synthesized at room temperature using the modified Stöber method combined with potassium borohydride (KBH4) reduction process. The present study depicts the facile synthesis of Fe@SiO2 without the presence of surfactants and stabilizers. In this experiment, KBH4 acted both as a reducing agent for iron salt and a catalyst for hydrolysis and polycondensation of tetraethylorthosilicate (TEOS).
View Article and Find Full Text PDFUnlabelled: In this study, Bacillus subtilis spores expressing a chimeric protein, CotB-VP28, were used as a probiotic vaccine to protect black tiger shrimps (Penaeus monodon) against white spot syndrome virus (WSSV) infection. Oral administration of pellets coated with CotB-VP28 spores (at ≥1 × 10 CFU per g pellet) to shrimps induced immune-relating phenoloxydase activity (PO) in shrimps after 14 days of feeding (prior challenge) and at day 3 post challenge (1·26 and 1·70 fold increase respectively). A 75% protection rate was obtained by continuous feeding of the spore-coated pellets at ≥1 × 10 CFU per g for 14 days prior to WSSV challenge and during all the postchallenge period.
View Article and Find Full Text PDFBackground: X-linked agammaglobulinemia (XLA) is a primary immune deficiency characterized by recurrent bacterial infections and profoundly depressed serum immunoglobulin levels and circulating mature B cells. It is caused by mutations of the Bruton tyrosine kinase (BTK) gene and is the most common form of inherited antibody deficiency. To our knowledge, this is the first report of XLA from Vietnam.
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