Publications by authors named "Asya Tucker"
Life Sci Alliance
February 2019
Article Synopsis
- Cardiomyopathy is a major concern in Duchenne muscular dystrophy, with mineralocorticoid and glucocorticoid receptors playing distinct roles in heart and muscle issues.
- The drug vamorolone can act as an MR antagonist and a unique GR ligand, reducing inflammation and offering better safety compared to prednisone.
- In studies on mice, vamorolone effectively prevents harmful effects linked to MR activation, unlike prednisolone, which worsens symptoms of cardiomyopathy.
