Publications by authors named "Aswathy Shailaja"

Article Synopsis
  • Brain injury is closely linked to preterm birth, with complications like intestinal perforations contributing to long-term neurological issues that are not well understood.
  • The study found that subventricular zone echogenicity (SVE) on cranial ultrasound in preterm infants after intestinal perforations was associated with motor impairment at age 2.
  • Research in a neonatal mouse model showed that SVE involves specific cellular changes, suggesting that ultrasound detection of SVE could be an early indicator of neurodevelopmental impairment in preterm infants experiencing inflammatory conditions.
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Filamentous fungi are ubiquitous and frequent components of biofilms. A means to visualize them and quantify their viability is essential for understanding their development and disruption. However, quantifying filamentous fungal biofilms poses challenges because, unlike yeasts and bacteria, they are not composed of discrete cells of similar size.

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Globally, cancer is amongst the most deadly diseases due to the low efficiency of the conventional and obsolete chemotherapeutic methodologies and their many downsides. The poor aqueous solubility of most anticancer medications and their low biocompatibility make them ineligible candidates for the design of delivery systems. A significant drawback associated with chemotherapy is that there are no advanced solutions to multidrug resistance, which poses a major obstacle in cancer management.

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Pathogenic viruses with an RNA genome represent a challenge for global human health since they have the tremendous potential to develop into devastating pandemics/epidemics. The management of the recent COVID-19 pandemic was possible to a certain extent only because of the strong foundations laid by the research on previous viral outbreaks, especially Ebola Virus Disease (EVD). A clear understanding of the mechanisms of the host immune response generated upon viral infections is a prime requisite for the development of new therapeutic strategies.

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