Publications by authors named "Aswathy K Vijayan"
Introduction: Oral lichen planus (OLP) is a chronic inflammatory disease with cell-mediated immune dysregulation. The aetiology of OLP has been studied extensively for decades. Viruses like Hepatitis C Virus (HCV), human papillomavirus (HPV), herpes simplex virus (HSV), and stress have been hypothesized to play a role in the pathogenesis and malignant transformation of OLP.
View Article and Find Full Text PDFObjective: Based on the modified diagnostic criteria for oral lichen planus (OLP) proposed by Van der Meij and Van der Waal, the objective of the current investigation was to demonstrate a clinicohistopathological association in the diagnosis of OLP.
Materials And Methods: Data were retrieved from 250 individuals who visited the Department of Oral Medicine and Radiology and were diagnosed with OLP between September 2018 and December 2021. Upon completion of the histopathological analysis, the precise diagnosis of OLP was made.
Background: Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory lesion of unknown cause. The buccal mucosa is the most frequently affected anatomic site and the lesion is bilateral. The objective of this retrospective study was to investigate the epidemiological and clinical characteristics of 250 OLP patients in South Kerala.
View Article and Find Full Text PDFObjective: The objective of the study was to use polymerase chain reaction (PCR) to examine and compare the genotype distribution of human papillomavirus (HPV) in oral lichen planus (OLP).
Materials And Methods: Deoxyribonucleic acid (DNA) was extracted from 20 OLP biopsy specimens. Conventional PCR assay employing consensus HPV primers was used to identify HPV DNA.
Article Synopsis
- - The study compares the effectiveness of conventional film and photostimulable phosphor (PSP) imaging in detecting interproximal caries by using a stereomicroscope for direct measurement as a reference.
- - A sample of 200 proximal surfaces from 100 extracted teeth was analyzed, with three observers evaluating both imaging methods, and the study found good agreement among observers with kappa coefficients ranging from 0.8788 to 0.9583.
- - The results showed that while PSP had slightly better specificity (80%) compared to film (78.3%), there were no significant differences in diagnostic ability between the two methods, leading to the recommendation of PSP for detecting cavitated proximal caries, pending further research on
Lichen planus (LP) is a chronic inflammatory mucocutaneous disease. The disease has a cell-mediated immune reaction which is precipitated by a specific trigger which turns the self-peptides antigenic. The role of human papillomavirus (HPV) in the malignant transformation of oral LP (OLP) has always been debated.
View Article and Find Full Text PDFArticle Synopsis
- - The study examines the effectiveness of photo stimulable phosphor (PSP) in detecting interproximal caries, comparing it to the precision of direct measurements taken with a stereomicroscope.
- - Researchers radiographed 100 proximal surfaces from 50 extracted human teeth using a digital X-ray system and classified caries lesions based on a 4-point scale.
- - Results show that the diagnostic accuracy of PSP is comparable to that of the stereomicroscope, suggesting that PSP is a viable option for detecting proximal caries, but more extensive research with additional evaluators is recommended.