Publications by authors named "Asunta Martinez-Martinez"
Article Synopsis
- Women's fertility declines significantly between the ages of 35-40 due to decreased ovarian activity and challenges in achieving pregnancy, both naturally and via assisted reproductive technologies.
- A systematic review of 142 studies from PubMed was conducted to explore the effects of age on the uterus and endometrium, focusing specifically on reproductive outcomes related to embryo transfers from younger egg donors.
- Results showed that advanced maternal age leads to a thinner endometrium and negatively impacts key fertility metrics, such as implantation and live birth rates, largely due to changes in uterine structure and hormone production.
Predicting risk of endometrial failure: a biomarker signature that identifies a novel disruption independent of endometrial timing in patients undergoing hormonal replacement cycles.
Patricia Diaz-Gimeno Patricia Sebastian-Leon Katharina Spath Diana Marti-Garcia Josefa Maria Sanchez-Reyes Asunta Martinez-Martinez
Fertil Steril
August 2024
Objective: To propose a new gene expression signature that identifies endometrial disruptions independent of endometrial luteal phase timing and predicts if patients are at risk of endometrial failure.
Design: Multicentric, prospective study.
Setting: Reproductive medicine research department in a public hospital affiliated with private fertility clinics and a reproductive genetics laboratory.