Publications by authors named "Asumi Daijo"
Int J Mol Sci
January 2019
Article Synopsis
- The study explores how endoplasmic reticulum (ER) stress affects the function of beige adipocytes, specifically their ability to regulate thermogenesis through uncoupling protein 1 expression.
- It was found that ER stress, induced by tunicamycin, significantly suppresses uncoupling protein 1 in inguinal white adipose tissue (IWAT), impacting the metabolic functions of adipocytes.
- The research identifies that ERK and JNK pathways are activated during ER stress; however, only JNK inhibition could restore the levels of peroxisome proliferator-activated receptor γ (Pparγ), which plays a crucial role in the expression of uncoupling protein 1
