Publications by authors named "Astrid K Lausdahl"
Article Synopsis
- The study examines the link between oxidative stress, cytotoxic oligomers of the protein α-synuclein, and Parkinson's disease development, highlighting potential mechanisms involving lipid peroxidation and membrane disruption.
- Researchers created α-synuclein oligomers in the presence of a lipid peroxidation byproduct and used advanced imaging techniques to study their interaction with live cells.
- Findings show that these oligomers strongly interact with cellular organelles, causing protein immobilization, mitochondrial fragmentation, and associations with endosomal structures, indicating a direct connection between toxic α-syn aggregates and cellular membranes.
Effects of Chokeberries ( spp.) on Cytoprotective and Cardiometabolic Markers and Semen Quality in 109 Mildly Hypercholesterolemic Danish Men: A Prospective, Double-Blinded, Randomized, Crossover Trial.
Julie Sangild Anne Faldborg Cecilie Schousboe Maja Døvling Kaspersen Fedder Lars Porskjær Christensen Astrid Komal Lausdahl
J Clin Med
January 2023
Article Synopsis
- Participants (109 healthy men) received either Aronia or a placebo for 90 days, focusing on health outcomes like cholesterol levels, sperm quality, and antioxidant glutathione levels, with variations based on age, lifestyle, and dietary habits.
- Results showed that Aronia supplementation improved glutathione in men with low baseline levels and high coffee intake, reduced sperm DNA fragmentation and increased motile sperm in older and overweight men, and lowered cholesterol in younger men, but other health parameters showed no significant changes.