Inhibition of B-cell activating factor activity using active compounds from in the mechanism of nephrotic syndrome improvement: A computational approach.

Nephrotic syndrome, a multifaceted medical condition characterized by significant proteinuria, has recently prompted a reorientation of research efforts toward B-cell-mediated mechanisms. This shift underscores the pivotal role played by B-cells in its pathogenesis. The aim of this study was to explore potential therapeutic pathways, with specific attention given to compounds found in , including withanolides, such as physalins, which constitute one of the five distinct withanolide subgroups identified in .

Genitourinary tuberculosis in 2-year-old indonesian boy with malnutrition: A rare case.

Genitourinary tuberculosis is a primary target of hematogenous infections and is the most common site of extra-pulmonary tuberculosis. A 2-year-old Indonesian boy with genitourinary tuberculosis with family history of tuberculosis. Radiological work-ups show pulmonary miliary tuberculosis, complication of hydronephrosis and ureteral kinking.