Model-informed precision dosing of vancomycin via continuous infusion: a clinical fit-for-purpose evaluation of published PK models.

Background: Model-informed precision dosing is an innovative approach used to guide bedside vancomycin dosing. The use of Bayesian software requires suitable and externally validated population pharmacokinetic (popPK) models.

Objectives: This study aimed to identify suitable popPK models for a priori prediction and a posteriori forecasting of vancomycin in continuous infusion.