Publications by authors named "Astrid Beck"

Congenital cryptorchidism, also known as undescended testis, is the condition where one or both testes are not in place in the scrotum at birth and is one of the most common birth defects in boys. Temporal trends and geographic variation in the prevalence of cryptorchidism from 1% to 9% have been reported in prospective cohort studies. The testes develop in the abdominal cavity and descend to the scrotum in two phases, which should be completed by gestational week 35.

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Article Synopsis
  • Recent research indicates that males with gynaecomastia have a higher long-term risk of death, particularly when underlying health issues exist.
  • A study in Denmark tracked 23,429 men with gynaecomastia, revealing a 37% increased risk of all-cause mortality compared to age-matched controls.
  • Specific causes of death were linked to cancers and diseases of the circulatory, pulmonary, and gastrointestinal systems, with a notably high risk of liver disease.
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Background: Many endocrine disrupting chemicals (EDCs), for instance phthalates and benzophenones, are associated with adverse fertility outcomes and semen quality parameters.

Objective: To evaluate if concentrations of selected phthalate metabolites and benzophenones measured in follicular fluid are associated with fertility outcomes (i.e.

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Background: Adverse Childhood Experiences (ACEs) have been identified as a major public health challenge in Greenland. No previous studies have created a multi-item ACE- scale among an Arctic Indigenous population.

Objective: To develop a multi-item ACE-scale among Inuit youth in Greenland (the ACEIG scale).

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Maternal smoking in pregnancy may increase the risk of testicular germ cell cancer (TGCC) in offspring, but current evidence remains inconclusive. We performed a nested case-control study using cotinine measurements in maternal serum and amniotic fluid as a biomarker for tobacco exposure during pregnancy. A total of 654 males with maternal serum (n = 359, n  = 71/288) and/or amniotic fluid (n = 295, n  = 66/229) samples were included.

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Fragility fractures, resulting from low-energy trauma, occur in approximately 1 in 10 Danish women aged 50 years or older. Bilateral oophorectomy (surgical removal of both ovaries) may increase the risk of fragility fractures due to loss of ovarian sex steroids, particularly estrogen. We investigated the association between bilateral oophorectomy and risk of fragility fracture and whether this was conditional on age at time of bilateral oophorectomy, hormone therapy (HT) use, hysterectomy, physical activity level, body mass index (BMI), or smoking.

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Background: Depression and dementia confer substantial global health burdens, particularly in women. Understanding the association between depression and dementia may inform new targets for prevention and/or early intervention.

Objective: To investigate the association between depression in mid- and later-life and dementia (all-cause, Alzheimer's disease (AD) or vascular dementia (VaD)) in women.

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Background: Maternal exposure to cigarette smoke in pregnancy may play a role in the development of testicular cancer in offspring. An updated and comprehensive systematic review of the available evidence is needed.

Objective: To identify and evaluate current evidence on maternal exposure to cigarette smoke during pregnancy and testicular cancer in offspring.

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Article Synopsis
  • The study aimed to explore how maternal paraben levels in urine during the second trimester affect the size of newborns, looking specifically at differences between female and male offspring.
  • A total of 529 mother-child pairs were analyzed, with urine samples tested for various types of parabens and their concentrations linked to birth outcomes such as weight and head circumference.
  • Results indicated that higher levels of n-butylparaben in mothers correlated with lower birth sizes in females, while no significant effects were found for males or for other types of parabens.
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