Publications by authors named "Astrid Backhaus"
Article Synopsis
- Induced pluripotent stem cell-derived mesenchymal stromal cells (iMSCs) and their extracellular vesicles (iMSC-EVs) are being evaluated as alternatives to traditional primary mesenchymal stromal cells (hUCMSCs) for use in advanced therapies.
- The study found that iMSCs effectively regulate immune responses, showing similar abilities to hUCMSCs in controlling lymphocyte growth and promoting an anti-inflammatory environment.
- Furthermore, iMSC-EVs demonstrated both immunomodulatory and regenerative properties, with enhanced effects observed when iMSCs were treated with pro-inflammatory cytokines, highlighting their potential as therapeutic options.
