[Morphological study of lymphoid organs at early stages of experimental prostate carcinogenesis].

Aim: the aim of our study was to identify of structural transformations in the thymus and lymph nodes at the early stages of the development of an experimental prostate cancer.

Materials And Methods: Experiments were performed on 60 adult male CBA mice weighing 28-30 g. An experimental model of a prostate cancer was created by inoculating a diluted cell strain of Ehrlich Ascites Carcinoma cells into the prostatic parenchyma through midline laparotomy under ether anesthesia.

Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease.

Objective: To compare the clinical acceptability of micronized purified flavonoid fraction (MPFF) 1000 mg with MPFF 500 mg tablets, administered at the same daily dose in patients suffering non-complicated acute hemorrhoids.

Background: MPFF is an established treatment for hemorrhoidal disease.

Methods: This was a double-blind, multi-center, randomized study.

Recombination of Correlations between Bioelements in the Liver and Lungs during Modeling of Diet-Induced Obesity.

In rats with obesity induced by high fat ration, the concentrations of K, Ca, Mn, Fe, Cu, Zn, Se, Br, Rb, and Sr were measured in the liver and lungs using synchrotron X-ray fluorescence analysis. Recombinations of inter-element correlations in the liver and lungs of rats receiving or not receiving additional Zn were observed under fasting conditions and after eating lard. Sr and Ca made the most pronounced contribution in the redistribution of correlations in the liver of obese rats.

Effect of zinc on the content of chemical elements in the lung tissue during obesity in the experiment.

We found no deviations from normalcy in the content of chemical elements (K, Ca, Mn, Fe, Cu, Zn, Se, Br, Rb, and Sr) in the lungs of rats with mild alimentary obesity, but revealed redistribution of correlations between the elements indicating impaired metabolism in this organ. Zinc supplementation had no effect on the body weight and content of chemical elements (including zinc) in the lung tissue in rats fed high fat diet, but led to significant changes in the correlations between the elements. Bromine, rubidium, and strontium are actively involved in interelement interactions in the lung tissue.

Thymus in experimental carcinogenesis of the prostate gland.

We studied structural changes in the prostate gland, thymus, and lymph nodes in CBA mice after transplantation of Ehrlich ascites tumor cells into the prostate gland. On experimental day 5, the number of blood and lymph vessels decreased in the gland; the percentage of connective tissue elements and glandular tissue and the number of immunoblasts in the thymus increased. On day 18, the number of blood vessels in the tumor decreased; the width of the cortex and glandular tissue increased in the thymus, while the number of immunoblasts was reduced.

[About the treatment of battlefield injuries of the musculoskeletal system with the help of new "Rod field package"].

Injuries of the musculoskeletal system are at 60% of all battlefield injures and take first place in modern military conflicts. The main antishock measures are: pain management, emergency bleeding control, bone fragment positioning and fracture fixation. Specialist of the centre of traumatology and orthopaedics of the Burdenko General Military Clinical Hospital in cooperation with specialists of department of battlefield surgery of Mandryka Clinical Research and Training Medical Centre analysed the most effective domestic and foreign external fixators and developed Rod field package (RFP).

[Application of high technology in liver surgery].

The PlasmaJet, a modem device that provides a high energy flow of ionized gas which seals small blood and lymph vessels has been recently introduced into clinical practice. A comparative retrospective analysis of results of 59 liver surgery with the help of new surgical technologies and standard surgical technique was performed. Liver resection with the use of high technology was accompanied by significantly less intraoperative blood loss, as well as a significant decrease of postoperative complications.

Effects of zinc on the content of chemical elements in the liver of rats during early stages of obesity.

In rats with slight alimentary obesity, the content of chemical elements in the liver did not differ from normal, but the correlations between these elements were changed, which attested to metabolic disorders. Additional zinc dose administered to rats receiving lipid-rich rations did not affect animal body weights and content of chemical elements (including zinc) in the liver, but corrected correlations between the elements. Active contribution of strontium, bromine, and rubidium to interactions between the elements in the liver necessitates studies of their role in biological processes, specifically, in initiation and development of obesity.

[Variants of retroperitoneal vascular structure in patients with early-stage cervical cancer who underwent systematic paraaortic and pelvic lymphadenectomy].

The aim of this study was to identify variants of retroperitoneal vascular structure during systematic paraaortic lymphadenectomy in patients with early-stage cervical cancer and to investigate the effects of these anomalies in surgical procedures. 79 patients who had undergone systematic paraaortic and bilateral pelvic lymph node dissection between 2006 and 2013 were included. Normal architecture and structural anomalies of inferior vena cava, renal arteries and veins, common iliac vein and ovarian vessels were studied.

Micronutrients and macronutrients in the liver in experimental alimentary obesity.

Strong and very strong positive correlations differing from those in the control were found between chemical elements in the liver of rats with experimental alimentary obesity under conditions of physiological hunger and soon after fatty food intake. These findings attest to sustained metabolism disturbances in obesity and formation of a pathological system. Considering the appearance of strong and very strong correlations of Br and Rb in alimentary obesity, more attention should be paid to the investigation of the role of these poorly studied elements in lipid metabolism.

[Essential elements (Fe, Cu, Mn, Zn, Se, As) in the liver and lungs with alimentary obesity in the experiment].

The purpose - to establish the role of lungs in the metabolic processes in normal and alimentary obesity. The method of X-ray fluorescence analysis using synchrotron radiation, the determination of concentrations Fe, Cu, Mn, Zn, Se, As in the tissue of the lungs and liver in 19 control rats and 19 rats with alimentary obesity. On the basis of many strengths and very strong positive correlation between the content of chemical elements shows that in the control rats, fasting metabolism in the lung more intense than the liver, which in case of obesity is significantly reduced.

[Role of the lungs in utilization of triglycerides from blood plasma after administration of fat in norm and experimental obesity].

The experiment was carried out on 72 rats (36 control and 36 with alimentary adiposity). There were established the absence of distinctions in concentration of triglyceride in plasma of blood from the right auricle and a carotid at rats with adiposity in 2 hours after the unitary use of lard in comparison with control rats. Plasma of blood from the right auricle of control animals contained more triglyceride and this facts indirectly testifies to decrease of their recycling in lungs at adiposity.

[Impact of purified drinking water use on the small bowel lymphatic region].

The structures of the mesenteric lymph nodes, small bowel, microvascular bed, and a mast cell population of the mesentery of rats were studied by light microscopy. Tap water, filtered water, and macro- and microelement-balanced water were used. The use of the filtered and macro- and micro-element water caused increases in lymph transport in the mesenteric lymph nodes and in the height of small intestinal villi, activated humoral immunity, and produced the most optimum level of a mast cell population and the structure of the mesenteric microvascular bed.

Hemolymphomicrocirculatory bed of the pancreas during acute experimental pancreatitis.

Histochemical study of rat pancreas was carried out on days 14 and 30 of acute pancreatitis. The area of the stroma increased after damage and the area of lymph microcirculatory component increased in comparison with the blood circulation component.

[Sanatorium rehabilitation of patients with chronic prostatitis].

A total of 75 males from married couples with circulatory prostatitis aged 19-47 were examined and treated in Barnaulsky sanatorium. The patients were trained by walking with the load power 80-110 W for 2.5 to 3 hours.

[The treatment of ulcerative gastrointestinal hemorrhages in the middle-aged and elderly].

Under analysis were results of treatment of 123 patients, 60 years of age and older who had ulcerous gastro-intestinal bleedings. Emergency operations were performed on 46 patients, postponed operations on 30 patients and there were 47 planned operations. Out of 38 patients operated upon for resection of the stomach 5 patients had incompetent sutures of the stomach and duodenum, 4 patients had purulent complications, 9 patients died.

[The structural organization of the regional lymph nodes of the heart in the acute period of experimental myocardial ischemia].

Anterior mediastinal and popliteal lymph nodes were studied morphologically and cytologically in male Wistar line rats in an acute period of experimental ischemia resulting from ligation of the left coronary artery. Three stages of structural-functional changes were demonstrated. In first stage increase of cortical substance square, widening of intermediate sinuses and macrophage number increase in all lymph node zones were observed in both groups after ligation of the artery.

[Study of blood and lymph in experimental myocardial ischemia and arterial hypertension].

The peripheral blood and central lymph of rats under experimental myocardial infarction was studied by means of light microscopy and electric conductivity measurement. Both hypertensive rats and animals 3 days after myocardial infarction had similar quantity of neutrophils in peripheral blood. Lymph cells count of hypertensive rats by middle lymphocytes is similar to the animals 1 day after myocardial infarction.

[Blood flow in the popliteal lymph node region of rats in experimental myocardial ischemia and its treatment with dog-rose polyphenols].

The regional blood flow in the distal part of the rat great adductor muscle was measured using polarographic method in the norm, under the condition of experimental myocardial infarction and after treatment with dog-rose polyphenols preparation. Maximal decrease of the regional blood flow was detected on the third day after the operation and it was recovered on the seventh day. The treatment led to normalization of the regional blood flow.