Phase separation drives the folding of recombinant collagen.

Recombinantly produced collagens present a sustainable, ethical, and safe substitute for collagens derived from natural sources. However, controlling the folding of the recombinant collagens, crucial for replicating the mechanical properties of natural materials, remains a formidable task. Collagen-like proteins from willow sawfly are relatively small and contain no hydroxyprolines, presenting an attractive alternative to the large and post-translationally modified mammalian collagens.

Early post-septal myectomy outcomes for hypertrophic obstructive cardiomyopathy.

Background: We aimed to evaluate early outcomes of septal myectomy in patients with hypertrophic cardiomyopathy.

Methods: We retrospectively analyzed data collected over a 9-year period from 583 patients who underwent septal myectomy for hypertrophic cardiomyopathy at our institution.

Results: The mean age was 55.

Rigid Ring Versus Flexible Band for Tricuspid Valve Repair in Patients Scheduled for Mitral Valve Surgery: A Prospective Randomised Study.

Background: Tricuspid valve repair for functional regurgitation is effectively performed with different annuloplasty devices. However, it remains unclear whether there are advantages associated with rigid rings compared to flexible bands. This prospective randomised study aimed to compare results of using a flexible band ring versus a rigid ring for functional tricuspid regurgitation in patients undergoing mitral valve surgery.

Myectomy versus alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy.

Objectives: There is very little evidence comparing the safety and efficacy of alcohol septal ablation versus septal myectomy for a septal reduction in patients with hypertrophic obstructive cardiomyopathy. This study aimed to compare the immediate and long-term outcomes of these procedures.

Methods: Following propensity score matching, we retrospectively analysed outcomes in 105 patients who underwent myectomy and 105 who underwent septal ablation between 2011 and 2017 at 2 reference centres.

[Experience of Treatment of Spontaneous Rupture of Left Ventricular Posterior Wall After Mitral Valve Replacement].

Spontaneous rupture of the left ventricular posterior wall after mitral valve replacement is a severe complication and is associated with high mortality rate. This complication was first described in 1967 by Roberts and Morrow, which describe the results of autopsy of two patients. In leading clinics around the world left ventricular wall ruptures after mitral valve replacement account for up to 20% of causes of hospital mortality.

[Aortic valve replacement with stentless bioprosthesis: surgical technique and early outcomes].

Aim: To evaluate prospectively the hemodynamic performance of «BiolAB Mono» stentless bioprosthesis implanted into aortic position.

Material And Methods: Twenty seven patients (mean age 71 (67; 73); 17 women) with severe aortic stenosis underwent, aortic valve replacement with «BioLAB Mono» stentless bioprosthesis from 2012 to 2014. The valves- were implanted into supraannular position using continuous polypropylene suture.

[Aortic valve replacement with stentless bioprosthesis].

Aim: To evaluate prospectively the hemodynamic performance of «BioLAB Mono» stentless bioprosthesis implanted into aortic position.

Material And Methods: Twenty seven patients (mean age 71 (67; 73); 17 women) with severe aortic stenosis underwent aortic valve replacement with «BioLAB Mono» stentless bioprosthesis from 2012 to 2014. The valves were implanted into supra-annular position using continuous polypropylene suture.

[The mithral valve replacement with biological prostheses: early and long-term results].

442 patients underwent the mitral valve replacement (MVR) with KemCor and PeriCor stented bioprostheses. The study results justified the preference of the "totally biological" PeriCor valve in patients with active infectious endocarditis. The longest follow-up period was 11 years, the mean follow-up was 51±34 months.

[A case of severe intravascular hemolysis after double mechanical heart valve implantation].

A case report of a patient with a triple cardiac valve replacement complicated by severe postoperative intravascular hemolysis is presented. The patient had neither prosthetic valvular dysfunction nor paravalvular leak and had an excellent hemodynamic response to the operation. Replacement of the aortic and mitral prostheses with stented porcine prosthesis alleviated the problem.

[The study of microcirculation in walls of chambers of the heart in patients with aortic stenosis in dependence on heart failure stage].

We studied microcirculatory blood flow (MBF) by laser Doppler flowmetry (LDF) in 52 patients with stage III-IV aortic stenosis (AS) and class II-IV chronic heart failure (CHF). MBF was assessed in walls of right and left cardiac chambers before and after correction of the defect. Aim of this study was to assess functional state of MBF in walls of different chambers of the heart before and after defect correction in patients with AS at various stages of CHF.

[Comparative characteristics of quality of life and physical status of patients with ischemic heart disease and aortic valve disease].

For comparison of physical status and quality of life of patients we analyzed 2 clinical groups: patients with ischemic heart disease (IHD) and aortic valve disease. Using original methodology of bringing results of questionnaire " Nottingham Health Profile " to functional classification we had a possibility to compare quality of life of patients with functional classes of physical working capacity and NYHA classification. Subjective component inserted into NYHA classification and quality of life questionnaire leads to substantial discrepancy with objective data on physical working capacity.