Publications by authors named "Assunta Castiello"

Article Synopsis
  • The study investigates the significance of TAPSE/PASP measurements in predicting outcomes for patients hospitalized with acute heart failure (AHF).
  • It found that lower TAPSE/PASP values were associated with more severe patient conditions and a higher risk of adverse outcomes, including death or hospitalization due to heart failure.
  • The research concludes that TAPSE/PASP is a valuable prognostic tool for assessing risks in AHF patients upon admission.
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Article Synopsis
  • - The study focused on how a patient's history of heart failure (HF) affects their prognosis after undergoing a MitraClip procedure for secondary mitral regurgitation (SMR), analyzing data from 186 patients across four centers.
  • - It found that patients with more than one HF hospitalization before the procedure experienced more severe symptoms and had a higher risk of clinical events, while other factors like the duration of hospitalization and timing of HF diagnoses did not significantly impact prognosis.
  • - After the MitraClip procedure, there was a notable decrease in both the number of hospitalizations and the total days spent in the hospital for HF within the following year, reinforcing that a history of recurrent HF hospitalizations is a strong predictor of patient outcomes.
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Aims: The aim of this study was to evaluate the safety and efficacy of the EkoSonic Endovascular System (EKOS) in patients with acute pulmonary embolism (APE) at high or intermediate-high risk and contraindication to systemic fibrinolysis.

Methods: This is a retrospective study including consecutive patients admitted due to high-risk or intermediate-high-risk APE and treated by EKOS because of an absolute or relative contraindication to systemic fibrinolysis. The primary efficacy end-point was the change from baseline to 72 h in right to left ventricular dimension ratio [right ventricular/left ventricular (RV/LV) ratio]; pulmonary embolic burden using the Qanadli Index; and systolic pulmonary arterial pressure (SPAP).

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The case deals with an anaphylactoid reaction to intravenous ampicillin/sulbactam resulting in cardiogenic syncope and myocardial damage. Symptoms and ECG modifications promptly disappeared after corticosteroids administration. The Kounis syndrome is an acute coronary syndrome, including coronary spasm, acute myocardial infarction and stent thrombosis, resulting from an anaphylactic or anaphylactoid or allergic or hypersensitivity insult.

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Background: Hypertension is strongly related to arterial stiffness in a cause-effect fashion. Diabetes mellitus is also thought to determine vascular damage, mostly by means of advanced glycosylation end-products (AGEs). Aim of our study was to study the role of type 2 diabetes mellitus (T2DM) as regard ascending aortic elastic properties in hypertensive patients.

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