Synthesis, Properties and Spatial Structure of 4-[(3,5-Dimethyl-1,2-oxazol-4-yl)sulfonyl]cytisine.

This article has studied the synthesis of a new derivative of the known alkaloid cytisine contained in the seeds of plants of Cytisus laburnum L. and Thermopsis lanceolata R.Br.

Synthesis, Structure and Molecular Docking of New 4,5-Dihydrothiazole Derivatives Based on 3,5-Dimethylpyrazole and Cytisine and Salsoline Alkaloids.

The interaction results of 1,2-dibromo-3-isothiocyanatopropane with some pyrazoles as well as cytisine and salsoline alkaloids were presented in this paper. It was shown that the reaction resulted in one one-step and rather mild method for the preparation of the corresponding 1,3-thiazoline bromomethyl derivatives. The yield of this reaction was affected by the presence of a base and an order in which reagents were added.

Determination of the Product of DNA Oxidation in the Blood of Women Living in the Sub-Aral Area.

To assess the impact of climatic and anthropogenic factors of the Aral Sea region on reproductive health, we examined 300 women living in the Kyzylorda region of Kazakhstan, which borders the Aral Sea region. The survey was based on comprehensive clinical-functional and laboratory studies accounting on regional environmental and ecological factors. The survey subject was the area of 2 settlements in Kyzylorda region.

The Study of Cellular and Molecular Physiological Characteristics of Sperm in Men Living in the Aral Sea Region.

Background: Extreme environmental situation in the Aral crisis has caused a massive chemical pollution of the territory for decades with high doses of pesticides, herbicides. Discharge of industrial waste into the rivers that feed the Aral Sea has lead to the development of various pathological processes in the human body, as well as disruption of reproductive function in young men.

Aim: To evaluate the performance of molecular cellular changes in the sperm of men under the influence of dust and salt aerosols in Aral Sea region.