Automatic identification of clinically relevant regions from oral tissue histological images for oral squamous cell carcinoma diagnosis.

Identification of various constituent layers such as epithelial, subepithelial, and keratin of oral mucosa and characterization of keratin pearls within keratin region as well, are the important and mandatory tasks for clinicians during the diagnosis of different stages in oral cancer (such as precancerous and cancerous). The architectural variations of epithelial layers and the presence of keratin pearls, which can be observed in microscopic images, are the key visual features in oral cancer diagnosis. The computer aided tool doing the same identification task would certainly provide crucial aid to clinicians for evaluation of histological images during diagnosis.

Automated identification of normoblast cell from human peripheral blood smear images.

In this paper, we have presented a new computer-aided technique for automatic detection of nucleated red blood cells (NRBCs) or normoblast cell from peripheral blood smear image. The proposed methodology initiates with the localization of the nucleated cells by adopting multilevel thresholding approach in smear images. A novel colour space transformation technique has been introduced to differentiate nucleated blood cells [white blood cells (WBCs) and NRBC] from red blood cells (RBCs) by enhancing the contrast between them.

Automated identification of keratinization and keratin pearl area from in situ oral histological images.

Oral squamous cell carcinoma (OSCC) has contributed 90% of oral cancer worldwide. In situ histological evaluation of tissue sections is the gold standard for oral cancer detection. Formation of keratinization and keratin pearl is one of the most important histological features for OSCC grading.

Structural and textural classification of erythrocytes in anaemic cases: a scanning electron microscopic study.

The objective of this study is to address quantitative microscopic approach for automated screening of erythrocytes in anaemic cases using scanning electron microscopic (SEM) images of unstained blood cells. Erythrocytes were separated from blood samples and processed for SEM imaging. Thereafter, erythrocytes were segmented using marker controlled watershed transformation technique.