Publications by authors named "Asmaa Sleem"
The emergence of methicillin-resistant (MRSA) several years ago highlighted the challenge of multidrug-resistant infections, emphasizing the critical need for innovative treatment approaches. Myrtenol, known for its antibacterial and antibiofilm properties, holds promise as a potential treatment option. This study aimed to evaluate the effectiveness of myrtenol against MRSA.
View Article and Find Full Text PDFIntroduction: The host genetic background is a crucial factor that underlies the interindividual variability of COVID-19 fatality and outcomes. Angiotensin-converting enzyme-2 () and interferon-induced transmembrane protein-3 () have a key role in viral cell entrance and priming. The evoked immune response will also provide a predictive prognosis for COVID-19 infection.
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- The study explores the potential of long noncoding RNAs (lncRNAs) LINC00152 and UCA1 as biomarkers for diagnosing and predicting outcomes in hepatocellular carcinoma (HCC).
- Serum levels of LINC00152 and UCA1 were significantly higher in HCC patients compared to those with liver cirrhosis and healthy individuals, indicating they can effectively differentiate between these groups.
- LINC00152 levels were associated with poorer outcomes in HCC patients, suggesting it might serve as a useful prognostic indicator, while both lncRNAs show promise as non-invasive diagnostic tools for HCC.
Background: Vitiligo is an acquired depigmented skin disorder. It has a genetic and autoimmune background. Human beta defensin-1(HBD-1) plus its gene polymorphism were linked to some autoimmune disorders.
View Article and Find Full Text PDFBackground And Aims: Reports examine quinolone resistance mechanisms among spp. are sporadic in the Kingdom of Saudi Arabia (KSA). We previously examined the genetic bases of plasmid-mediated quinolone resistance among spp.
View Article and Find Full Text PDFBackground: S100A8 single nucleotide polymorphism (SNP) and S100A8 blood level are related to many inflammatory disorders with no available conclusion in psoriasis.
Aim: The aim of this study was to evaluate the possible role of S100A8 in psoriasis pathogenesis through analyzing its S100A8 (rs3806232) gene polymorphism and S100A8 serum level in psoriasis vulgaris patients, in addition to correlate the detected results with severity psoriasis in those patients.
Methods: This case-control study was conducted on 50 patients having psoriasis vulgaris, and 26 controls.