Cadmium-induced pancreatic toxicity in rats: comparing vitamin C and as protective agents: a histomorphometric and ultrastructural study.

The study aimed to assess the toxic effect of cadmium (Cd) on the exocrine and endocrine functions of pancreas, the changes in pancreatic tissue after Cd withdrawal, and the protective effects of vitamin C (VC) and () against Cd-induced damage. Rats were assigned to: control, Cd-treated (0.5mg/kg/d intraperitoneal [IP] injection), VC and Cd-treated (receiving 100 mg/kg/d VC orally and Cd concomitantly), and Cd-treated (receiving 20 mg/kg/d and Cd, simultaneously), and Cd withdrawal (receiving Cd for 30 d then living free for recovery for other 30 d).

Expression profile of serum LncRNAs and and their correlation with Mayo severity score in ulcerative colitis patients can diagnose and predict the prognosis of the disease.

Background: Ulcerative colitis (UC) has emerged as an accelerated-incidence chronic condition. UC has been identified as a precancerous lesion for colorectal cancer. Up-to-date genomic research revealed the value of many noncoding RNAs (ncRNAs) in UC pathogenesis, diagnosis, and prognosis.