Background And Objectives: The type I interferon (IFN) signature has been found to be overactivated in many systemic autoimmune diseases. This may be explained by impaired regulation of interferon-stimulated genes (ISGs) as well as interferon-induced protein 44 (IFI44) expression via their regulatory mechanisms via interferon regulatory factors (IRFs).
Patients And Methods: This case-control study includes two groups: 50 RA patients and 50 healthy controls.
Aging-related sarcopenia is a degenerative loss of strength and skeletal muscle mass that impairs quality of life. Evaluating NUDT3 gene and myogenin expression as new diagnostic tools in sarcopenia. Also, comparing the concomitant treatment of resistance exercise (EX) and creatine monohydrate (CrM) versus single therapy by EX, coenzyme Q10 (CoQ10), and CrM using aged rats.
View Article and Find Full Text PDFPost-transcriptional modifications of RNA play a key role in performing a variety of biological processes, such as stability and immune tolerance, RNA splicing, protein translation and RNA degradation. One of these RNA modifications is m5c which participates in various cellular functions like RNA structural stability and translation efficiency, got popularity among biologists. By applying biological experiments to detect RNA m5c methylation sites would require much more efforts, time and money.
View Article and Find Full Text PDFObjectives: This study aimed to examine the association between the effect of emotional intelligence on job burn-out and the mediating effect of workplace conflict management among critical care physicians.
Design And Setting: A cross-sectional study design was deployed.
Participants: The studied sample comprised 144 critical care physicians working at two Egyptian tertiary care public hospitals.
This study presents an enhanced deep learning approach for the accurate detection of eczema and psoriasis skin conditions. Eczema and psoriasis are significant public health concerns that profoundly impact individuals' quality of life. Early detection and diagnosis play a crucial role in improving treatment outcomes and reducing healthcare costs.
View Article and Find Full Text PDFSolid waste workers are exposed to variety of injuries and diseases at work. To study health disorders among workers in the waste management field and to assess their knowledge attitude and practice (KAP) towards hazardous exposure and safety measures. A cross-sectional study was carried out on 275 waste workers and an equal number as a group of controls from workers' relatives or workers not involved in waste management.
View Article and Find Full Text PDFWork is a social double edged weapon activity that may have positive and negative effects on individual's quality of life and health. To estimate workaholism prevalence and to determine its effects on quality of life, mental health, and burnout among healthcare workers (HCWs). Using a cross-sectional study, 1,080 Egyptian participants distributed as HCWs and non-HCWs were recruited.
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