Sensitive and highly selective colorimetric biosensing of vitamin-C and vitamin-B1 by flavoring agent-based silver nanoparticles.

A sensitive scheme was established for the detection of vitamin C (Ascorbic acid) and vitamin B1 (Thiamin HCl) using Maltol capped AgNPs (McAgNPs) as colorimetric sensor. The designed scheme showed an instant alteration in color from yellow to orange and green for vitamin-C and vitamin B1 sequentially. The probe was sensitive in a concentration range of (0-1 µM) with limit of detection 0.

meningitis due to external ventricular drain.

Introduction: is a rare non-tuberculous organism associated with catheter-related infections when pathogenic in humans. We present the first case of an external ventricular drain (EVD)-associated meningitis.

Case Presentation: A 55-year-old woman had EVD placement for obstructive hydrocephalus following traumatic subarachnoid haemorrhage.

Seroprevalence of anti-SARS-CoV-2 antibodies in residents of Karachi-challenges in acquiring herd immunity for COVID 19.

Background: The recent pandemic by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global emergency. There is large number of asymptomatic cases of SARS-CoV-2 that are not reported. Hence, serological evidence of SARS-CoV2 antibodies is warranted for a better estimation of the actual number of infected patients to limit the disease spread and to get an idea of herd immunity.

Incidence of Venous Thromboembolism in Critically Ill Coronavirus Disease 2019 Patients Receiving Prophylactic Anticoagulation.

Objectives: One of the defining features of the novel coronavirus disease 2019 infection has been high rates of venous thromboses. The present study aimed to describe the prevalence of venous thromboembolism in critically ill patients receiving different regimens of prophylactic anticoagulation.

Design: Single-center retrospective review using data from patients with confirmed severe acute respiratory syndrome coronavirus 2 requiring intubation.

Synthesis and characterization of maltol capped silver nanoparticles and their potential application as an antimicrobial agent and colorimetric sensor for cysteine.

Maltol capped silver nanoparticles (McAgNPs) were synthesized using maltol (3-hydroxy-2-methyl-4-pyrone) as reducing and capping agent. McAgNPs were characterized by Visible and FTIR (Fourier transform infrared) spectroscopy, dynamic light scattering (DLS), and atomic force microscopy (AFM). Bright yellow color McAgNPs showed surface plasmon resonance (SPR) band at 436 nm, spherical shape and the average size between 35 to 50 nm.

Synthesis and sensitive detection of doxycycline with sodium bis 2-ethylhexylsulfosuccinate based silver nanoparticle.

The monitoring of residual antibiotics in the environment has gained a significant importance for the effective control, because of the high risk to human health. A simple strategy was designed for the green synthesis and detection of doxycycline (Dox) by using anionic surfactant sodium bis 2-ethylhexylsulfosuccinate based silver nanoparticles (AOT-AgNPs). The chemical reduction and capping of Ag ions was achieved by sulfonyl and carbonyl functional groups of AOT molecule.

Duplication cyst of the pylorus: a rare cause of gastric outlet obstruction.

Alimentary tract duplications are a rare congenital malformation. They can present with varied symptoms owing to the locality of the duplication, along the gastrointestinal tract. Out of these duplications, the ones along the pylorus are the most rare.

Ameliorating effect of Allium Sativum on high-fat diet induced fatty liver in albino rats.

Objective: To assess the hepatoprotective effect provided by fresh garlic on fatty liver induced by high-fat diet.

Methods: This experimental study was carried out at BMSI, JPMC from October to November 2008. Thirty adult albino rats, 200-240 gram weight, were divided into three groups.

Fresh garlic amelioration of high-fat-diet induced fatty liver in albino rats.

Objective: To observe the effect of fresh garlic on high-fat-diet-induced fatty liver changes.

Methods: The experimental study was conducted at the Jinnah Postgraduate Medical Centre, Karachi, from October to November 2008, and comprised adult albino rats weighing 200-240g each. The rats were divided into 5 groups according to dietary regimen for eight weeks each.

Prevalence of quinolone-resistant urinary tract infections in Comanche County Memorial Hospital.

Purpose: Urinary tract infection (UTI) is not only a common outpatient but also the most frequently occurring nosocomial infection. The most common causative organisms of UTI remain Escherichia coli, nosocomial gram-negative bacilli, enteroccoci and candida. Many physicians use quinolones as the agent of choice for treatment of UTI.

Perforated appendicitis: accuracy of ct diagnosis and correlation of ct findings with the length of hospital stay.

Objective: To determine the sensitivity and specificity of CT findings in the differentiation of perforated from nonperforated appendicitis and correlate CT diagnosis with the length of hospital stay.

Study Design: An analytical study.

Place And Duration Of Study: This study was conducted at Radiology Department of Aga Khan University Hospital, Karachi, from January 2004 to June 2005.

Role of magnetic resonance imaging in lumbar spondylosis.

Objective: To assess the frequency of various MRI findings in patients with lumbar spondylosis and determine their association with symptoms of patients.

Design: Cross-sectional analytical study.

Place And Duration Of Study: Radiology Department,The Aga Khan University Hospital, Karachi, from January to December, 2002.

Sebaceous carcinoma of the oral mucosa: case report and review of the literature.

Fordyce granules are found in the oral mucosa of up to 80% of adults. However, primary malignant sebaceous tumors of the oral mucosa are exceedingly rare. To our knowledge, only 5 examples of intraoral sebaceous carcinoma have been reported in the literature.